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- W3029786146 abstract "目的 探讨出生～学龄前小儿脊柱的生长发育规律及椎体生长板血管内皮生长因子(VEGF)的表达与作用.方法选择35例0～6岁发育正常的小儿T8(含上、下生长板的完整椎体)标本,在4倍光镜下用显微尺测量椎体骨质的绝对厚度(不包括生长板和椎间盘);用免疫组化ABC法对T8生长板VEGF的表达及分布规律进行观察并用图像分析仪进行定量研究.结果同一椎体(T8)骨质厚度值测定结果:第一年内增加了0.22cm(44%),第二年内增加了0.15cm(21%),第三年内增加了0.07cm(8%),第四年内增加了0.04cm(4%),第五年内增加了0.02cm(2%),第六年内增加了0.01cm(1%).各年龄组椎体生长板均能表达VEGF,但呈逐年减低.结论出生后～5岁前是脊柱第一个生长发育高峰期;椎体生长板ⅥEGF的表达集中在肥大细胞层下半区及临时钙化层;VEGF是生长板生长活性可靠的测量指标,能够很好的反映其所处的成骨状态。" @default.
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- W3029786146 date "2004-04-05" @default.
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- W3029786146 title "Experimental study on spinal growth and expression of vascular endothelial growth factor (VEGF) in the vertebral growth plate" @default.
- W3029786146 doi "https://doi.org/10.3760/cma.j.issn.0253-3006.2004.02.023" @default.
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