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- W3029804787 abstract "ObjectiveTo assess the postoperative pituitary tumor endocrine metabolic disturbance, and analyze the treatment effect of hormone replacement therapy.MethodsSeventy-eight patients with hypophysoma treated from June 2013 to February 2014 were selected as the research objects. They underwent selective pituitary tumor surgery, the free triiodothyronine (FT3), thyrotrophin (TSH), free thyroid hormone (FT4), cortisol (PTC), adrenocorticotro (ACTH) levels before the operation, postoperative 3 d, postoperative 3 months, postoperative 1 year were compared, the patients with hypopituitarism within postoperative 3 d were given left thyroid hormone and metacortandracin to conduct replacement therapy, the treatment effects of hormone replacement therapy within 1 year were analyzed, and the adverse reactions were observed.ResultsThe levels of FT3 [(2.18±0.96)mol/L], TSH [(0.57±0.32)mU/L], FT4 [(11.42±2.15)pmol/L], PTC [(0.16±0.02)μmol/L], ACTH [(6.31±1.59)ng/L] of patients postoperative 3 d were significantly lower than those before operation, postoperative 3 months, postoperative 1 year (P 0.05); hypopituitarism occurred in 50 cases after the operation, the occurrence rate was 64.10%, and the effective rate of hormone replacement therapy was 86.00%, the incidence of adverse reactions was 10.00%.ConclusionsAdenohypophysis endocrine metabolic disturbance occur in postoperative pituitary tumor patients, timely monitoring is needed especially in postoperative 3 d, and conduct hormone replacement therapy.Key words: Pituitary tumor surgery; Endocrine; Estimation; Hormone; Replacement therapy" @default.
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- W3029804787 date "2017-02-25" @default.
- W3029804787 modified "2023-09-28" @default.
- W3029804787 title "Assessment of postoperative pituitary tumor endocrine metabolic disturbance and effect of hormone replacement therapy" @default.
- W3029804787 doi "https://doi.org/10.3760/cma.j.issn.1674-4756.2017.04.015" @default.
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