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- W3029805105 abstract "Fragile X syndrome is a common cause of inherit mental retardation,GABAA receptors are the major inhibitory neurotransmitter receptros in the mammalian central nervous system, implicated in anxiety,depression, epilepsy, sleeping problem, learning and memory, and so on. Several researches indicated that the GABAergic system, in particular the GABAA receptors might be related to the phenotype of fragile X syndrome. An altered expression of certain subunits of the GABAA receptors may cause the neurological and behavioural changes of the fragile X syndrome. Therefore,the GABAA receptors can be a novel therapeutic target for treatment of fragile X syndrome.Key words: Fragile X syndrome; GABAA receptors; Phenotype" @default.
- W3029805105 created "2020-06-05" @default.
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- W3029805105 date "2010-11-26" @default.
- W3029805105 modified "2023-09-24" @default.
- W3029805105 title "GABAA receptors and fragile X syndrome" @default.
- W3029805105 doi "https://doi.org/10.3760/cma.j.issn.1673-4408.2010.06.029" @default.
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