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- W3029808585 abstract "ObjectiveTo assess the difference in left atrial properties between elderly and younger control subjects and the role of left atrium remodeling in patients of different ages with atrial fibrillation.MethodsA total of 194 patients with non-valvular atrial fibrillation were enrolled from September 2014 to June 2016.Based on age, patients were divided into an elderly group (≥60 years, n=129) and a younger group (<60 years, n=65). We evaluated remodeling parameters for the left atrium using an Ultrasound Cardiography (UCG) system in 125 elder subjects, together with 64 control subjects.All remodeling parameters were recorded, including left atrial diameter (LAD), left atrial square (LAS), left atrial pressure (LAP) and left ventricular end-diastolic dimension (LVEDD).ResultsThe elderly group had more female patients and more patients with persistent atrial fibrillation.Meanwhile, scores of CHA2DS2Vsc and levels of N-terminal pro-brain natriuretic peptide (NT-ProBNP) were significantly increased in elderly patients (both P<0.05). Moreover, the elderly group was associated with increased values of LAD and LAS〔(39.1±4.4)mm vs.(37.1±5.3)mm, P<0.01; and(23.3±4.5)cm2vs.(21.4±4.8)cm2, P<0.01; respectively〕, compared with those in the control group.Spearman’s correlation analysis showed that LAD, LAS and LAP were all markedly related to age (r=0.213, P<0.05; r=-0.175, P<0.05; r=0.170, P<0.05; respectively), persistent onset of atrial fibrillation (r=0.401, P<0.05; r=0.446, P<0.05; r=0.160, P<0.05; respectively), and impaired heart function, measured by left ventricular ejection fraction (r=-0.4371, P<0.05; r=-0.403, P<0.05; r=-0.364, P<0.05; respectively) and NT-ProBNP (r=0.485, P<0.01; r=0.483, P<0.01; r=0.293, P<0.01; respectively).ConclusionsLeft atrial remodeling properties measured by the UCG system in the elderly with non-valvular atrial fibrillation are more serious than those in mid-aged and young subjects.As a convenient and accurate assessment of remodeling parameters, the UCG system is an excellent option for measuring left atrial remodeling in the elderly population.Key words: Atrial fibrillation; Echocardiography" @default.
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- W3029808585 date "2017-11-14" @default.
- W3029808585 modified "2023-09-28" @default.
- W3029808585 title "The evaluation of structural remodeling of the left atrium in elderly patients with non-valvular atrial fibrillation" @default.
- W3029808585 doi "https://doi.org/10.3760/cma.j.issn.0254-9026.2017.11.001" @default.
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