FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3029845229> ?p ?o ?g. }

• W3029845229 endingPage "66" @default.
• W3029845229 startingPage "59" @default.
• W3029845229 abstract "Females suffer from depression at twice the rate of males and have differential neural and emotional responses to inflammation. However, sex-specific evaluation of relationships between inflammation and response to depression treatments are lacking. Some data suggest that interleukin(IL)-8 predicts treatment response to antidepressants and has a relationship with depressive symptom severity. This study examines whether IL-8 predicts treatment response to electroconvulsive therapy (ECT), and whether there are sex specific effects. In 40 depressed patients (22 female), plasma levels of IL-8, as well as other markers of inflammation including IL-6, IL-10, tumor necrosis factor (TNF)-α, and C-reactive protein (CRP) were obtained prior to administration of ECT and after completion of the index treatment series. Depression treatment response was defined as ≥ 50% reduction in Hamilton Depression Rating Scale (HAM-D) Score. Baseline levels of IL-8 differed by responder status, depending on sex (group × sex interaction: β = -0.571, p = 0.04), with female responders having lower levels of IL-8 at baseline as compared to female non-responders [t(20) = 2.37, p = 0.03]. Further, IL-8 levels from baseline to end of treatment differed by responder status, depending on sex (group × sex × time interaction: [F(1,36) = 9.48, p = 0.004]), and change in IL-8 from baseline to end of treatment was negatively correlated with percentage change in HAM-D score in females (β = -0.458, p = 0.03), but not in males (β = 0.315, p = 0.20). Other inflammatory markers did not differ in relation to responder status and sex. Further evaluation of sex differences in the relationship between IL-8, depression, and treatment response, across disparate treatment modalities, may inform mechanisms of response and aid in development of personalized medicine strategies." @default.
• W3029845229 created "2020-06-05" @default.
• W3029845229 creator A5005936736 @default.
• W3029845229 creator A5010368679 @default.
• W3029845229 creator A5012747700 @default.
• W3029845229 creator A5029927032 @default.
• W3029845229 creator A5031702769 @default.
• W3029845229 creator A5043625675 @default.
• W3029845229 creator A5045027912 @default.
• W3029845229 creator A5048442564 @default.
• W3029845229 creator A5066725766 @default.
• W3029845229 creator A5068266222 @default.
• W3029845229 creator A5083948964 @default.
• W3029845229 date "2020-10-01" @default.
• W3029845229 modified "2023-10-18" @default.
• W3029845229 title "Inflammation and depression treatment response to electroconvulsive therapy: Sex-specific role of interleukin-8" @default.
• W3029845229 cites W1487916236 @default.
• W3029845229 cites W1587456727 @default.
• W3029845229 cites W1894734502 @default.
• W3029845229 cites W1967445338 @default.
• W3029845229 cites W1969065116 @default.
• W3029845229 cites W1969476117 @default.
• W3029845229 cites W1972878959 @default.
• W3029845229 cites W1981407617 @default.
• W3029845229 cites W1981907384 @default.
• W3029845229 cites W1981934038 @default.
• W3029845229 cites W1985438873 @default.
• W3029845229 cites W1989369404 @default.
• W3029845229 cites W1996024251 @default.
• W3029845229 cites W1997422264 @default.
• W3029845229 cites W2003982930 @default.
• W3029845229 cites W2007116949 @default.
• W3029845229 cites W2013794551 @default.
• W3029845229 cites W2016575029 @default.
• W3029845229 cites W2030957288 @default.
• W3029845229 cites W2032919221 @default.
• W3029845229 cites W2034040263 @default.
• W3029845229 cites W2044767152 @default.
• W3029845229 cites W2049785594 @default.
• W3029845229 cites W2051359369 @default.
• W3029845229 cites W2053020615 @default.
• W3029845229 cites W2074515925 @default.
• W3029845229 cites W2090213741 @default.
• W3029845229 cites W2091259554 @default.
• W3029845229 cites W2091623121 @default.
• W3029845229 cites W2092669597 @default.
• W3029845229 cites W2114058973 @default.
• W3029845229 cites W2114613490 @default.
• W3029845229 cites W2116496248 @default.
• W3029845229 cites W2122946630 @default.
• W3029845229 cites W2161161114 @default.
• W3029845229 cites W2162510673 @default.
• W3029845229 cites W2167314970 @default.
• W3029845229 cites W2200324439 @default.
• W3029845229 cites W2280318158 @default.
• W3029845229 cites W2297545252 @default.
• W3029845229 cites W2321830693 @default.
• W3029845229 cites W2339807712 @default.
• W3029845229 cites W2414491533 @default.
• W3029845229 cites W2549722103 @default.
• W3029845229 cites W2593014017 @default.
• W3029845229 cites W2605671917 @default.
• W3029845229 cites W2706345148 @default.
• W3029845229 cites W2734838975 @default.
• W3029845229 cites W2746917316 @default.
• W3029845229 cites W2766457937 @default.
• W3029845229 cites W2774812729 @default.
• W3029845229 cites W2791309385 @default.
• W3029845229 cites W2793187604 @default.
• W3029845229 cites W2807128602 @default.
• W3029845229 cites W2807318413 @default.
• W3029845229 cites W2808196202 @default.
• W3029845229 cites W2808599394 @default.
• W3029845229 cites W2895214689 @default.
• W3029845229 cites W2900473935 @default.
• W3029845229 cites W2906735570 @default.
• W3029845229 cites W2922705509 @default.
• W3029845229 cites W2933795674 @default.
• W3029845229 cites W2952070206 @default.
• W3029845229 cites W2954242481 @default.
• W3029845229 cites W2969919519 @default.
• W3029845229 cites W3171418018 @default.
• W3029845229 cites W581977681 @default.
• W3029845229 doi "https://doi.org/10.1016/j.bbi.2020.05.069" @default.
• W3029845229 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7572496" @default.
• W3029845229 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32479994" @default.
• W3029845229 hasPublicationYear "2020" @default.
• W3029845229 type Work @default.
• W3029845229 sameAs 3029845229 @default.
• W3029845229 citedByCount "20" @default.
• W3029845229 countsByYear W30298452292021 @default.
• W3029845229 countsByYear W30298452292022 @default.
• W3029845229 countsByYear W30298452292023 @default.
• W3029845229 crossrefType "journal-article" @default.
• W3029845229 hasAuthorship W3029845229A5005936736 @default.
• W3029845229 hasAuthorship W3029845229A5010368679 @default.
• W3029845229 hasAuthorship W3029845229A5012747700 @default.
• W3029845229 hasAuthorship W3029845229A5029927032 @default.

• next