Matches in SemOpenAlex for { <https://semopenalex.org/work/W3029893329> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W3029893329 endingPage "327" @default.
- W3029893329 startingPage "323" @default.
- W3029893329 abstract "Background Retinal development continues during the early postnatal period in mammals.Correct arrangement of layers and precise location of various cells in the retina are vital for forming normal visual function during critical period plasticity.Spectral-domain optical coherence tomography(SD-OCT)provides highquality in vivo retinal imaging and the possibility to measure retinal thickness longitudinally. Objective The present study was to investigate the changes of retinal thickness during critical period plasticity in rats. Methods In vivo consecutive scanning of retinal image was performed in 10 SPF Sprague-Dawley rats at postnatal day 14(P14),P18,P21,P24 and P42 with SD-OCT,and retinal histopathological examination was used to detect retinal morphologic changes at the same postnatal ages in 20 matched rats.The whole retinal thickness,the thickness from inner limiting membrane(ILM)to inner plexiform layer(IPL),the thickness of inner nuclear layer(INL)and the thickness from outer nuclear layer(ONL)to retinal pigment epithelium(RPE)were measured using Cirrus HD-OCT system and HMIAS-2000 Imaging System in retinal sections.The measurement parameters by Cirrus HD-OCT and those by hematoxylin-eosin staining were compared.The use of animals followed the Statement of National Institute of Health (USA). Results In vivo high-resolution images of rat retinas with SD-OCT compared well with histology,which enabled quantitative comparison of the SD-OCT and histological data during critical period plasticity in rats.From P14 to P42,the retinal thickness gradually decreased with the increase of rat ages(F=15.425,P=0.000),and so were the thickness from ILM to IPL,the thickness of INL and the thickness from ONL to RPE(F=3.973,P=0.007;F=17.529,P=0.000;F=7.038,P=0.000).The retinal thickness,thickness of INL.thickness from ONL to RPE measured by Cirrus HD-OCT were significantly correlated with those measured by retinal sections among P14,P18,P21,P24 and P42 rats(r=0.794,P=0.000;r=0.784,P=0.000;r=0.681,P=0.000). Conclusion SD-OCT is a demonstratably valuable technology to study the structure of retinas in rats.The retinal thickness is shown to reduce in thickness throughout the development of the retina during critical period plasticity due to the decrease in thickness of INL and the distance from the ONL to RPE,as illustrated by OCT scanning.Key words: Retina; Optical coherence tomography/spectral-domain:Critical Period Plasticity" @default.
- W3029893329 created "2020-06-05" @default.
- W3029893329 creator A5001329524 @default.
- W3029893329 creator A5015524637 @default.
- W3029893329 creator A5032066559 @default.
- W3029893329 creator A5050387132 @default.
- W3029893329 creator A5056640120 @default.
- W3029893329 creator A5073593485 @default.
- W3029893329 date "2011-04-10" @default.
- W3029893329 modified "2023-09-27" @default.
- W3029893329 title "Dynamic change of spectral-domain optical coherence tomography in rat retina during critical period plasticity" @default.
- W3029893329 doi "https://doi.org/10.3760/cma.j.issn.2095-0160.2011.04.009" @default.
- W3029893329 hasPublicationYear "2011" @default.
- W3029893329 type Work @default.
- W3029893329 sameAs 3029893329 @default.
- W3029893329 citedByCount "0" @default.
- W3029893329 crossrefType "journal-article" @default.
- W3029893329 hasAuthorship W3029893329A5001329524 @default.
- W3029893329 hasAuthorship W3029893329A5015524637 @default.
- W3029893329 hasAuthorship W3029893329A5032066559 @default.
- W3029893329 hasAuthorship W3029893329A5050387132 @default.
- W3029893329 hasAuthorship W3029893329A5056640120 @default.
- W3029893329 hasAuthorship W3029893329A5073593485 @default.
- W3029893329 hasConcept C105702510 @default.
- W3029893329 hasConcept C118487528 @default.
- W3029893329 hasConcept C169760540 @default.
- W3029893329 hasConcept C2777093970 @default.
- W3029893329 hasConcept C2777506830 @default.
- W3029893329 hasConcept C2777585161 @default.
- W3029893329 hasConcept C2778024200 @default.
- W3029893329 hasConcept C2778231335 @default.
- W3029893329 hasConcept C2778818243 @default.
- W3029893329 hasConcept C2780098626 @default.
- W3029893329 hasConcept C2780827179 @default.
- W3029893329 hasConcept C71924100 @default.
- W3029893329 hasConcept C86803240 @default.
- W3029893329 hasConceptScore W3029893329C105702510 @default.
- W3029893329 hasConceptScore W3029893329C118487528 @default.
- W3029893329 hasConceptScore W3029893329C169760540 @default.
- W3029893329 hasConceptScore W3029893329C2777093970 @default.
- W3029893329 hasConceptScore W3029893329C2777506830 @default.
- W3029893329 hasConceptScore W3029893329C2777585161 @default.
- W3029893329 hasConceptScore W3029893329C2778024200 @default.
- W3029893329 hasConceptScore W3029893329C2778231335 @default.
- W3029893329 hasConceptScore W3029893329C2778818243 @default.
- W3029893329 hasConceptScore W3029893329C2780098626 @default.
- W3029893329 hasConceptScore W3029893329C2780827179 @default.
- W3029893329 hasConceptScore W3029893329C71924100 @default.
- W3029893329 hasConceptScore W3029893329C86803240 @default.
- W3029893329 hasIssue "04" @default.
- W3029893329 hasLocation W30298933291 @default.
- W3029893329 hasOpenAccess W3029893329 @default.
- W3029893329 hasPrimaryLocation W30298933291 @default.
- W3029893329 hasRelatedWork W1018609964 @default.
- W3029893329 hasRelatedWork W1862576678 @default.
- W3029893329 hasRelatedWork W1928896080 @default.
- W3029893329 hasRelatedWork W1980870010 @default.
- W3029893329 hasRelatedWork W1989642498 @default.
- W3029893329 hasRelatedWork W1992171452 @default.
- W3029893329 hasRelatedWork W2012254759 @default.
- W3029893329 hasRelatedWork W2061477205 @default.
- W3029893329 hasRelatedWork W2086222521 @default.
- W3029893329 hasRelatedWork W2126851442 @default.
- W3029893329 hasRelatedWork W2259103970 @default.
- W3029893329 hasRelatedWork W2588845171 @default.
- W3029893329 hasRelatedWork W2734333901 @default.
- W3029893329 hasRelatedWork W2737861152 @default.
- W3029893329 hasRelatedWork W2763584550 @default.
- W3029893329 hasRelatedWork W2950910889 @default.
- W3029893329 hasRelatedWork W2996039697 @default.
- W3029893329 hasRelatedWork W3000697728 @default.
- W3029893329 hasRelatedWork W3040090327 @default.
- W3029893329 hasRelatedWork W3042113518 @default.
- W3029893329 hasVolume "29" @default.
- W3029893329 isParatext "false" @default.
- W3029893329 isRetracted "false" @default.
- W3029893329 magId "3029893329" @default.
- W3029893329 workType "article" @default.