FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3029901145> ?p ?o ?g. }

• W3029901145 endingPage "204201882092532" @default.
• W3029901145 startingPage "204201882092532" @default.
• W3029901145 abstract "This study aimed to determine the effect of moderate intensity continuous exercise (Ex) and hypoxia (Hyp) on serum brain-derived neurotrophic factor (BDNF), insulin-like growth factor-1 (IGF-1) and its binding protein-3 (IGFBP-3), irisin and cytokines levels in patients with type 1 diabetes (T1D).A total of 14 individuals with T1D (age: 28.7 ± 7.3 years) and 14 healthy adults (age: 27.1 ± 3.9 years) performed 40-min continuous Ex at moderate intensity (50% lactate threshold) on a cycle ergometer in normoxia (Nor) and Hyp (FiO2 = 15.1%) Biochemical factors, glucose concentrations and physiological variables were measured at rest, immediately and up to 24 h after both Ex protocols.Patients with T1D had significantly lower pre-Ex serum concentrations of BDNF (p < 0.05, p < 0.01), and total IGF-1 (p < 0.001, p < 0.05) and significantly higher irisin levels (p < 0.05, p < 0.01) in Nor and Hyp, compared with healthy subjects. Ex significantly increased in T1D group serum BDNF (in Nor only p < 0.05) and total IGF-1 levels in Nor and Hyp (p < 0.001 and p < 0.01, respectively). Immediately after Ex in Hyp, freeIGF-1 (p < 0.05) and irisin levels (p < 0.001) were significantly higher compared with the levels induced by Ex alone. Free IGF-1 and irisin serum levels remained elevated in 24 h post-Ex in Hyp. In T1D, significant blood glucose (BG) decrease was observed immediately after Ex in Hyp (p < 0.001) and in 24 h recovery (p < 0.001) compared with pre-Ex level.The study results suggest that moderate intensity continuous Ex has beneficial effect on BDNF and IGF-1 levels. Ex in hypoxic conditions may be more effective in increasing availability of IGF-1. The alterations in the post-Ex irisin levels and IGF-1 system may be contributing to more effective glycaemia control in patients with T1D." @default.
• W3029901145 created "2020-06-05" @default.
• W3029901145 creator A5006674640 @default.
• W3029901145 creator A5039992848 @default.
• W3029901145 creator A5055791708 @default.
• W3029901145 creator A5057049895 @default.
• W3029901145 creator A5060860262 @default.
• W3029901145 creator A5073090576 @default.
• W3029901145 creator A5091855378 @default.
• W3029901145 date "2020-01-01" @default.
• W3029901145 modified "2023-10-14" @default.
• W3029901145 title "Moderate intensity exercise in hypoxia increases IGF-1 bioavailability and serum irisin in individuals with type 1 diabetes" @default.
• W3029901145 cites W1564586175 @default.
• W3029901145 cites W1924912806 @default.
• W3029901145 cites W1966813815 @default.
• W3029901145 cites W1969713762 @default.
• W3029901145 cites W1971254161 @default.
• W3029901145 cites W1986161305 @default.
• W3029901145 cites W1986295350 @default.
• W3029901145 cites W1994208622 @default.
• W3029901145 cites W1995381409 @default.
• W3029901145 cites W1995861797 @default.
• W3029901145 cites W2000249408 @default.
• W3029901145 cites W2002198217 @default.
• W3029901145 cites W2005959327 @default.
• W3029901145 cites W2006891931 @default.
• W3029901145 cites W2015991601 @default.
• W3029901145 cites W2021262492 @default.
• W3029901145 cites W2023411705 @default.
• W3029901145 cites W2025069550 @default.
• W3029901145 cites W2026185164 @default.
• W3029901145 cites W2063264522 @default.
• W3029901145 cites W2074531985 @default.
• W3029901145 cites W2083119172 @default.
• W3029901145 cites W2087338218 @default.
• W3029901145 cites W2092114693 @default.
• W3029901145 cites W2096691898 @default.
• W3029901145 cites W2098178035 @default.
• W3029901145 cites W2103488083 @default.
• W3029901145 cites W2109145353 @default.
• W3029901145 cites W2109474508 @default.
• W3029901145 cites W2111181526 @default.
• W3029901145 cites W2113216859 @default.
• W3029901145 cites W2114083304 @default.
• W3029901145 cites W2114280375 @default.
• W3029901145 cites W2135213520 @default.
• W3029901145 cites W2144606783 @default.
• W3029901145 cites W2153797344 @default.
• W3029901145 cites W2169091672 @default.
• W3029901145 cites W2176938578 @default.
• W3029901145 cites W2185623954 @default.
• W3029901145 cites W2254392117 @default.
• W3029901145 cites W2266543467 @default.
• W3029901145 cites W2277107211 @default.
• W3029901145 cites W2292431366 @default.
• W3029901145 cites W2321363491 @default.
• W3029901145 cites W2331753718 @default.
• W3029901145 cites W2393403573 @default.
• W3029901145 cites W2411722506 @default.
• W3029901145 cites W2471605942 @default.
• W3029901145 cites W2536270858 @default.
• W3029901145 cites W2538435828 @default.
• W3029901145 cites W2541593044 @default.
• W3029901145 cites W2571775490 @default.
• W3029901145 cites W2589143196 @default.
• W3029901145 cites W2609559846 @default.
• W3029901145 cites W2612535417 @default.
• W3029901145 cites W2755572978 @default.
• W3029901145 cites W2756097722 @default.
• W3029901145 cites W2759105955 @default.
• W3029901145 cites W2770565967 @default.
• W3029901145 cites W2779917149 @default.
• W3029901145 cites W2792501508 @default.
• W3029901145 cites W2802240112 @default.
• W3029901145 cites W2803137866 @default.
• W3029901145 cites W2884396167 @default.
• W3029901145 cites W2889012161 @default.
• W3029901145 cites W2892986281 @default.
• W3029901145 cites W2894566075 @default.
• W3029901145 cites W2896323318 @default.
• W3029901145 cites W2900652426 @default.
• W3029901145 cites W2901998029 @default.
• W3029901145 cites W2904914426 @default.
• W3029901145 cites W2953214438 @default.
• W3029901145 cites W2958483210 @default.
• W3029901145 cites W3004348632 @default.
• W3029901145 cites W4213210402 @default.
• W3029901145 cites W4242554702 @default.
• W3029901145 doi "https://doi.org/10.1177/2042018820925326" @default.
• W3029901145 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7257872" @default.
• W3029901145 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32523674" @default.
• W3029901145 hasPublicationYear "2020" @default.
• W3029901145 type Work @default.
• W3029901145 sameAs 3029901145 @default.
• W3029901145 citedByCount "9" @default.
• W3029901145 countsByYear W30299011452020 @default.
• W3029901145 countsByYear W30299011452021 @default.
• W3029901145 countsByYear W30299011452023 @default.

• next