Matches in SemOpenAlex for { <https://semopenalex.org/work/W3029907169> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W3029907169 endingPage "60" @default.
- W3029907169 startingPage "57" @default.
- W3029907169 abstract "Objectives To investigate protective effect of recombinant human erythropeietin (rhEPO) on acute renal ischemia-reperfusion injury(IR/I) in rats.Methods Twenty one male S-D rats were randomly divided into 3 groups:Sham,IR/I,rhEPO(injection via intraperitoneal 2 h before surgery at the dosages of 1000U/kg).Rat model of renal IR/I was established with clamping both pedicles for 45 min followed by reperfusion.Blood sample and kidneys were collected at indicated times.Serum creatinine levels,urea nitrogen,histological change and mortality were observed throughout the study.ELISA was used to measure the levels of serum vascular endothelial growth factor(VEGF).The expression of heme oxygenase-1 (HO-1) in kidney observed by Immunohistochemical.Results Extensive proximal tubular necrosis,functional impairment and higher mortality were found repeffusion after 24 hours in IR/I group (P ＜ 0.01).Elevated serum VEGF levels and increased expression of HO-1 protein in kidney were significantly higher than IR/I group and sham group(P ＜ 0.01).Conclusions thEPO can attenuate renal IR/I.The protection mechanisms may be through the anti-oxidation and to promote renal tubular epithelial cell regeneration.Key words: Reperfusion Injury; Kidney; failure ; Rats; Erythropoietion, Recombinant" @default.
- W3029907169 created "2020-06-05" @default.
- W3029907169 creator A5011987859 @default.
- W3029907169 creator A5035088788 @default.
- W3029907169 creator A5078031834 @default.
- W3029907169 date "2013-01-15" @default.
- W3029907169 modified "2023-09-23" @default.
- W3029907169 title "Protective effect of recombinant human erythropoietin on renal ischemia reperfusion injury in rats" @default.
- W3029907169 doi "https://doi.org/10.3760/cma.j.issn.1673-4416.2013.01.020" @default.
- W3029907169 hasPublicationYear "2013" @default.
- W3029907169 type Work @default.
- W3029907169 sameAs 3029907169 @default.
- W3029907169 citedByCount "0" @default.
- W3029907169 crossrefType "journal-article" @default.
- W3029907169 hasAuthorship W3029907169A5011987859 @default.
- W3029907169 hasAuthorship W3029907169A5035088788 @default.
- W3029907169 hasAuthorship W3029907169A5078031834 @default.
- W3029907169 hasConcept C104317684 @default.
- W3029907169 hasConcept C126322002 @default.
- W3029907169 hasConcept C134018914 @default.
- W3029907169 hasConcept C159641895 @default.
- W3029907169 hasConcept C167734588 @default.
- W3029907169 hasConcept C185592680 @default.
- W3029907169 hasConcept C204232928 @default.
- W3029907169 hasConcept C2777025900 @default.
- W3029907169 hasConcept C2778176769 @default.
- W3029907169 hasConcept C2778534260 @default.
- W3029907169 hasConcept C2780091579 @default.
- W3029907169 hasConcept C2780114680 @default.
- W3029907169 hasConcept C2780306776 @default.
- W3029907169 hasConcept C2780472472 @default.
- W3029907169 hasConcept C2780721119 @default.
- W3029907169 hasConcept C40767141 @default.
- W3029907169 hasConcept C503630168 @default.
- W3029907169 hasConcept C541997718 @default.
- W3029907169 hasConcept C55493867 @default.
- W3029907169 hasConcept C71924100 @default.
- W3029907169 hasConceptScore W3029907169C104317684 @default.
- W3029907169 hasConceptScore W3029907169C126322002 @default.
- W3029907169 hasConceptScore W3029907169C134018914 @default.
- W3029907169 hasConceptScore W3029907169C159641895 @default.
- W3029907169 hasConceptScore W3029907169C167734588 @default.
- W3029907169 hasConceptScore W3029907169C185592680 @default.
- W3029907169 hasConceptScore W3029907169C204232928 @default.
- W3029907169 hasConceptScore W3029907169C2777025900 @default.
- W3029907169 hasConceptScore W3029907169C2778176769 @default.
- W3029907169 hasConceptScore W3029907169C2778534260 @default.
- W3029907169 hasConceptScore W3029907169C2780091579 @default.
- W3029907169 hasConceptScore W3029907169C2780114680 @default.
- W3029907169 hasConceptScore W3029907169C2780306776 @default.
- W3029907169 hasConceptScore W3029907169C2780472472 @default.
- W3029907169 hasConceptScore W3029907169C2780721119 @default.
- W3029907169 hasConceptScore W3029907169C40767141 @default.
- W3029907169 hasConceptScore W3029907169C503630168 @default.
- W3029907169 hasConceptScore W3029907169C541997718 @default.
- W3029907169 hasConceptScore W3029907169C55493867 @default.
- W3029907169 hasConceptScore W3029907169C71924100 @default.
- W3029907169 hasIssue "01" @default.
- W3029907169 hasLocation W30299071691 @default.
- W3029907169 hasOpenAccess W3029907169 @default.
- W3029907169 hasPrimaryLocation W30299071691 @default.
- W3029907169 hasRelatedWork W1837355344 @default.
- W3029907169 hasRelatedWork W1982482424 @default.
- W3029907169 hasRelatedWork W1985012537 @default.
- W3029907169 hasRelatedWork W2064559166 @default.
- W3029907169 hasRelatedWork W2068335228 @default.
- W3029907169 hasRelatedWork W2082242605 @default.
- W3029907169 hasRelatedWork W2368562702 @default.
- W3029907169 hasRelatedWork W2381471106 @default.
- W3029907169 hasRelatedWork W2389152242 @default.
- W3029907169 hasRelatedWork W2392662098 @default.
- W3029907169 hasRelatedWork W2498984821 @default.
- W3029907169 hasRelatedWork W2973181845 @default.
- W3029907169 hasRelatedWork W3003250358 @default.
- W3029907169 hasRelatedWork W3032490665 @default.
- W3029907169 hasRelatedWork W3032516461 @default.
- W3029907169 hasRelatedWork W3032546023 @default.
- W3029907169 hasRelatedWork W3041921700 @default.
- W3029907169 hasRelatedWork W3117234953 @default.
- W3029907169 hasRelatedWork W3142182423 @default.
- W3029907169 hasRelatedWork W49709741 @default.
- W3029907169 hasVolume "33" @default.
- W3029907169 isParatext "false" @default.
- W3029907169 isRetracted "false" @default.
- W3029907169 magId "3029907169" @default.
- W3029907169 workType "article" @default.