FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3029942620> ?p ?o ?g. }

• W3029942620 endingPage "137" @default.
• W3029942620 startingPage "135" @default.
• W3029942620 abstract "A 29-year-old man with malignant pheochromocytoma was treated with oral apatinib 500 mg once daily. One week later, the apatinib was decreased 375 mg once daily due to increased blood pressure. Thirty-seven days after drug administration, he developed bloody stool 50 ml and apatinib was withdrawn. Four days later, the original dosage of apatinib was given because of disease progression. On day 9, he developed bloody stool 600 ml. On day 10, he developed bloody stool 2 300 ml and vomited coffee-ground-like gastric content about 1 000 ml. He received an IV pumping of octreotide acetate, IV infusions of hydroxyethyl starch 40 sodium chloride, carbazochrome sodium sulfonate, etamsylate and aminomethylbenzoic acid. Laboratory tests revealed the following levels: RBC 1.2×1012/L, Hb 37 g/L, thrombin time 17 s, prothrombin time 22 s, D-dimer 3.3 mg/L, calcium 1.22 mmol/L, potassium 2.5 mmol/L, total protein 26 g/L, albumin 15 g/L, creatinine 12 μmol/L, uric acid 29 μmol/L. Apatinib induced acute gastrointestinal hemorrhage was considered. Apatinib was withdrawn. He was given pressurized by intravenous infusion of suspended red blood cells, IV infusions of carbazochrome sodium sulfonate and glucose gluconate. The next morning, he experienced bloody stool 2 500 ml and vomited coffee-ground-like gastric content about 500 ml. He received oral lyophilized thrombin powder, pressurized by intravenous infusion of suspended red blood cells, IV infusions of dopamine hydrochloride and human albumin, intramuscular injection of vitamin K1, IV infusion of lansoprazole, etamsylate, aminome-thylbenzoic acid, pantoprazole sodium and fat emulsion amino acids (17) and glucose (11%). At the noon of the same day, he experienced melena about 80 g. He was given oral lyophilized thrombin powder. On day 2 after apatinib withdrawal, he experienced melena 30 g. On day 4, laboratory tests revealed the following levels again: RBC 2.6×1012/L, Hb 95 g/L, thrombin time 14 s, prothrombin time 16 s, D-dimer 1.9 mg/L, calcium 2.35 mmol/L, potassium 4.0 mmol/L, total protein 52 g/L, albumin 32 g/L, creatinine 28 μmol/L, uric acid 191 μmol/L. Nutrition supportive, liver and stomach protecting treatments continued, gastrointestinal hemorrhage did not recur.Key words: Gastrointestinal hemorrhage; Apatinib" @default.
• W3029942620 created "2020-06-05" @default.
• W3029942620 creator A5034669926 @default.
• W3029942620 creator A5048189895 @default.
• W3029942620 creator A5088883583 @default.
• W3029942620 date "2017-04-28" @default.
• W3029942620 modified "2023-10-03" @default.
• W3029942620 title "Acute gastrointestinal hemorrhage due to apatinib" @default.
• W3029942620 doi "https://doi.org/10.3760/cma.j.issn.1008-5734.2017.02.014" @default.
• W3029942620 hasPublicationYear "2017" @default.
• W3029942620 type Work @default.
• W3029942620 sameAs 3029942620 @default.
• W3029942620 citedByCount "0" @default.
• W3029942620 crossrefType "journal-article" @default.
• W3029942620 hasAuthorship W3029942620A5034669926 @default.
• W3029942620 hasAuthorship W3029942620A5048189895 @default.
• W3029942620 hasAuthorship W3029942620A5088883583 @default.
• W3029942620 hasConcept C121608353 @default.
• W3029942620 hasConcept C126322002 @default.
• W3029942620 hasConcept C2780668389 @default.
• W3029942620 hasConcept C42219234 @default.
• W3029942620 hasConcept C71924100 @default.
• W3029942620 hasConcept C90924648 @default.
• W3029942620 hasConceptScore W3029942620C121608353 @default.
• W3029942620 hasConceptScore W3029942620C126322002 @default.
• W3029942620 hasConceptScore W3029942620C2780668389 @default.
• W3029942620 hasConceptScore W3029942620C42219234 @default.
• W3029942620 hasConceptScore W3029942620C71924100 @default.
• W3029942620 hasConceptScore W3029942620C90924648 @default.
• W3029942620 hasIssue "2" @default.
• W3029942620 hasLocation W30299426201 @default.
• W3029942620 hasOpenAccess W3029942620 @default.
• W3029942620 hasPrimaryLocation W30299426201 @default.
• W3029942620 hasRelatedWork W1985108802 @default.
• W3029942620 hasRelatedWork W1985229569 @default.
• W3029942620 hasRelatedWork W2015142972 @default.
• W3029942620 hasRelatedWork W2031978957 @default.
• W3029942620 hasRelatedWork W2067272923 @default.
• W3029942620 hasRelatedWork W2077305683 @default.
• W3029942620 hasRelatedWork W2146717972 @default.
• W3029942620 hasRelatedWork W2353917179 @default.
• W3029942620 hasRelatedWork W2360671850 @default.
• W3029942620 hasRelatedWork W2394994554 @default.
• W3029942620 hasRelatedWork W2409594763 @default.
• W3029942620 hasRelatedWork W2413407893 @default.
• W3029942620 hasRelatedWork W2466855156 @default.
• W3029942620 hasRelatedWork W2469056281 @default.
• W3029942620 hasRelatedWork W2508113959 @default.
• W3029942620 hasRelatedWork W3028728224 @default.
• W3029942620 hasRelatedWork W3029275008 @default.
• W3029942620 hasRelatedWork W3029312888 @default.
• W3029942620 hasRelatedWork W3030297958 @default.
• W3029942620 hasRelatedWork W3031058009 @default.
• W3029942620 hasVolume "19" @default.
• W3029942620 isParatext "false" @default.
• W3029942620 isRetracted "false" @default.
• W3029942620 magId "3029942620" @default.
• W3029942620 workType "article" @default.