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- W3029962794 abstract "目的 对间质性肺疾病患者影像学、肺功能及临床表现进行相关分析,评价肺功能特别是脉冲振荡(IOS)测定呼吸阻抗在该疾病诊断中的意义.方法 对56例间质性肺疾病患者的呼吸阻抗、常规肺功能、静息时动脉血氧分压(PaO2)及肺部高分辨CT评分和呼吸困难评分进行分析.结果 振荡频率在5 Hz时的电抗(X5)、在20 Hz时的电抗(X20)与肺活量(VC)呈正相关(r=0.699、0.537,P＜0.05),与用力肺活量(FVC)呈正相关(r=0.690、0.473,P＜0.05),与一氧化碳弥散量(DLCO)呈正相关(r-=0.494、0.301,P＜0.05),与PaO2呈负相关(r=-0.621、-0.411,P＜0.05);响应频率与VC、FVC、DLCO呈负相关(r=-0.658、-0.639、-0.352,P＜0.05),与PaO2呈正相关(r=0.277,P＜0.05);特发性肺间质纤维化患者的病程较结缔组织病所致间质性肺疾病患者的病程明显延长(P＜0.05),其余观察指标差异无统计学意义(P＞0.05).结论 常规肺功能指标VC、FVC、DLCO及呼吸阻抗指标响应频率、X5对肺间质纤维化的诊断有一定的意义;IOS测定呼吸阻抗对间质性肺疾病患者肺功能损害的动态监测和疗效评价具有一定的应用前景;应重视结缔组织病患者的影像学和肺功能检查以便及时发现肺部早期病变。" @default.
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- W3029962794 date "2007-05-05" @default.
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- W3029962794 title "Correlation of pulmonary function measurements and high resolution computed tomography manifestations in patients with interstitial lung disease" @default.
- W3029962794 doi "https://doi.org/10.3760/cma.j.issn.1673-4904.2007.13.007" @default.
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