Matches in SemOpenAlex for { <https://semopenalex.org/work/W3030008744> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W3030008744 endingPage "22" @default.
- W3030008744 startingPage "18" @default.
- W3030008744 abstract "ObjectiveTo observe the clinical efficacy of genetic haploidentical peripheral blood stem cell transplantation on relapsed and refractory acute leukemia.MethodsThe clinical data of 57 patients with relapsed and refractory acute leukemia who accepted genetic haploidentical peripheral blood stem cell transplantation were retrospectively analyzed, including 43 cases of acute lymphoblastic leukemia (ALL), 14 cases of acute myeloid leukemia (AML). Haploidentical peripheral blood stem cell transplantation using modified BU/CY+ ATG ; applying cyclosporine A+ mycophenolate mofetil+ short-range methotrexate±basiliximab to prevent graft-versus-host disease.ResultsFifty-seven patients with relapsed and refractory acute leukemia were followed for an median of 32 months(2-65 months), infection rate of granulocyte lack period was 84.2%(48/57); the incidence of neutrophil reconstruction was 98.2%(56/57), the median implanted time was 14 d(10-22 d), the rate of platelet engraftment was 91.2%(52/57), median implanted time was 20 d(10-90 d); the incidence of GVHD was 61.4%(35/57), including acute GVHD [26.3%(15/57)], the incidence of chronic GVHD was 35.1%(20/57); the incidence of hemorrhagic cystitis was 36.8%(21/57); the recurrence rate after transplantation was 24.6%(14/57), 2 cases got posttransplant lymplaoproliferative disease; the nonrelapse mortality was 31.6%(18/57); 3 years overall survival was 44%, 3 year disease-free survival was 40%.ConclusionsIn the absence of HLA-identical siblings donors and unrelated donor, genetic haploidentical peripheral blood stem cell transplantation for treatment of relapsed and refractory acute leukemia is an effective and feasible method.Key words: Haploidentical hematopoietic stem cell transplantation; Acute leukemia; Recurrence rate; Disease-free survival" @default.
- W3030008744 created "2020-06-05" @default.
- W3030008744 creator A5005371991 @default.
- W3030008744 creator A5017755691 @default.
- W3030008744 creator A5019344762 @default.
- W3030008744 creator A5027883397 @default.
- W3030008744 creator A5051905686 @default.
- W3030008744 creator A5069847539 @default.
- W3030008744 creator A5073640749 @default.
- W3030008744 creator A5074811571 @default.
- W3030008744 creator A5080113481 @default.
- W3030008744 date "2017-03-10" @default.
- W3030008744 modified "2023-09-24" @default.
- W3030008744 title "Clinical analysis of genetic haploidentical peripheral blood stem cell transplantation on relapsed and refractory acute leukemia" @default.
- W3030008744 doi "https://doi.org/10.3760/cma.j.issn.1674-4756.2017.05.007" @default.
- W3030008744 hasPublicationYear "2017" @default.
- W3030008744 type Work @default.
- W3030008744 sameAs 3030008744 @default.
- W3030008744 citedByCount "0" @default.
- W3030008744 crossrefType "journal-article" @default.
- W3030008744 hasAuthorship W3030008744A5005371991 @default.
- W3030008744 hasAuthorship W3030008744A5017755691 @default.
- W3030008744 hasAuthorship W3030008744A5019344762 @default.
- W3030008744 hasAuthorship W3030008744A5027883397 @default.
- W3030008744 hasAuthorship W3030008744A5051905686 @default.
- W3030008744 hasAuthorship W3030008744A5069847539 @default.
- W3030008744 hasAuthorship W3030008744A5073640749 @default.
- W3030008744 hasAuthorship W3030008744A5074811571 @default.
- W3030008744 hasAuthorship W3030008744A5080113481 @default.
- W3030008744 hasConcept C120665830 @default.
- W3030008744 hasConcept C121332964 @default.
- W3030008744 hasConcept C126322002 @default.
- W3030008744 hasConcept C141071460 @default.
- W3030008744 hasConcept C142424586 @default.
- W3030008744 hasConcept C2776863199 @default.
- W3030008744 hasConcept C2777408962 @default.
- W3030008744 hasConcept C2778461978 @default.
- W3030008744 hasConcept C2778729363 @default.
- W3030008744 hasConcept C2781307858 @default.
- W3030008744 hasConcept C2909675724 @default.
- W3030008744 hasConcept C2911091166 @default.
- W3030008744 hasConcept C61511704 @default.
- W3030008744 hasConcept C71924100 @default.
- W3030008744 hasConcept C86803240 @default.
- W3030008744 hasConcept C87355193 @default.
- W3030008744 hasConcept C88879693 @default.
- W3030008744 hasConcept C90924648 @default.
- W3030008744 hasConceptScore W3030008744C120665830 @default.
- W3030008744 hasConceptScore W3030008744C121332964 @default.
- W3030008744 hasConceptScore W3030008744C126322002 @default.
- W3030008744 hasConceptScore W3030008744C141071460 @default.
- W3030008744 hasConceptScore W3030008744C142424586 @default.
- W3030008744 hasConceptScore W3030008744C2776863199 @default.
- W3030008744 hasConceptScore W3030008744C2777408962 @default.
- W3030008744 hasConceptScore W3030008744C2778461978 @default.
- W3030008744 hasConceptScore W3030008744C2778729363 @default.
- W3030008744 hasConceptScore W3030008744C2781307858 @default.
- W3030008744 hasConceptScore W3030008744C2909675724 @default.
- W3030008744 hasConceptScore W3030008744C2911091166 @default.
- W3030008744 hasConceptScore W3030008744C61511704 @default.
- W3030008744 hasConceptScore W3030008744C71924100 @default.
- W3030008744 hasConceptScore W3030008744C86803240 @default.
- W3030008744 hasConceptScore W3030008744C87355193 @default.
- W3030008744 hasConceptScore W3030008744C88879693 @default.
- W3030008744 hasConceptScore W3030008744C90924648 @default.
- W3030008744 hasIssue "5" @default.
- W3030008744 hasLocation W30300087441 @default.
- W3030008744 hasOpenAccess W3030008744 @default.
- W3030008744 hasPrimaryLocation W30300087441 @default.
- W3030008744 hasRelatedWork W1929057510 @default.
- W3030008744 hasRelatedWork W2068700346 @default.
- W3030008744 hasRelatedWork W20730027 @default.
- W3030008744 hasRelatedWork W2163309297 @default.
- W3030008744 hasRelatedWork W2359854925 @default.
- W3030008744 hasRelatedWork W2382852924 @default.
- W3030008744 hasRelatedWork W2549717966 @default.
- W3030008744 hasRelatedWork W2579311150 @default.
- W3030008744 hasRelatedWork W2743517177 @default.
- W3030008744 hasRelatedWork W2950784319 @default.
- W3030008744 hasRelatedWork W2992959047 @default.
- W3030008744 hasRelatedWork W2997065532 @default.
- W3030008744 hasRelatedWork W3024213900 @default.
- W3030008744 hasRelatedWork W3025084914 @default.
- W3030008744 hasRelatedWork W3029138910 @default.
- W3030008744 hasRelatedWork W3030666296 @default.
- W3030008744 hasRelatedWork W3030894017 @default.
- W3030008744 hasRelatedWork W3032251843 @default.
- W3030008744 hasRelatedWork W3032701155 @default.
- W3030008744 hasRelatedWork W3206619752 @default.
- W3030008744 hasVolume "44" @default.
- W3030008744 isParatext "false" @default.
- W3030008744 isRetracted "false" @default.
- W3030008744 magId "3030008744" @default.
- W3030008744 workType "article" @default.