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- W3030036565 abstract "Immunosuppresants commonly used in clinic at present, always play their roles in suppressing immune systems by taking effects on the typical immunocytes. Apart from the benefits, their practical value are however restricted by the intensively toxic and side effects. Many of the recent investigation, especially in the field of transplantation, have shown that, when combined mesenchymal stem cells (MSC) and low dose immunosuppresants, On one hand, the MSC can exert better immunomodulatory function, as well as significantly reduces the side effects of immunosuppressants. On the other hand, low dose of immunosuppressants may have different effects on the exertion of other functions of MSC. Here, we conclude the recent ten years of related research and make a discussion on the mechanism of the interaction between MSC and commonly used immunosuppresants.Key words: Mesenchymal stem cell; Tacrolimus; Sirolimus; Leflunomide; Cyclosporin A; Mycophenolate mofetil; Azathioprine; Arsenic trioxide" @default.
- W3030036565 created "2020-06-05" @default.
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- W3030036565 date "2018-06-08" @default.
- W3030036565 modified "2023-09-23" @default.
- W3030036565 title "Research progress in the interaction of mesenchymal stem cells and common immunosuppressants" @default.
- W3030036565 doi "https://doi.org/10.3760/cma.j.issn.1001-9030.2018.06.060" @default.
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