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- W3030106821 abstract "Pheochromocytomas and paragangliomas are tumors of the autonomic nervous system. It haspreviously been estimated that approximately 10% ～ 15% of pheochromocytomas are caused by hereditary, butrecent studies indicate that the frequencies of germline mutations in RET, VHL, SDHB, SDHD together approa-ches 30%. According to this situation, genetic testing is suggested. In this article the known genetic syndromesare commonly associated with pheochromocytoma, its genes'structure, germline mutations, the association be-tween the genotype and the phenotype, and the possible pathogenesis are reviewed.Key words: Pheochromocytoma; Molecular genetics; Gene" @default.
- W3030106821 created "2020-06-05" @default.
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- W3030106821 date "2009-06-15" @default.
- W3030106821 modified "2023-09-26" @default.
- W3030106821 title "Molecular Genetic Research of Pheochromocytoma" @default.
- W3030106821 doi "https://doi.org/10.3760/cma.j.issn.1673-4386.2009.03.007" @default.
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