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- W3030183417 abstract "ObjectiveTo evaluate the safety and efficacy of endoscopic ultrasonography (EUS) guided ethanol ablation in patients with insulinoma.MethodsThe data of 10 patients with insulinoma treated at the First Affiliated Hospital of Guangxi Medical University from December 2013 to January 2015 were prospectively analyzed.ResultsThe patients were given EUS-guided ethanol ablation with dose of 0.10 to 2.00 ml (average 0.70 ± 0.62 ml) in pancreatic lesions for 15 times. No complications were observed during and after the procedure. The blood glucose improved after the procedure [4.8(3.9-5.5) mmol/L VS 2.4(1.9-2.5) mmol/L, P<0.05] and the serum insulin level significantly decreased[83.7(40.1-143.5) pmol/L VS 177.3(66.5-200.6) pmol/L, P<0.05]. The average hospital stay was (4.3±1.5) days. The patients were followed up for 6-12 months. EUS indicated that the echo of pancreatic lesions changed from high to low. CE-EUS revealed low enhancement and lack of blood supply.ConclusionEUS-guided ethanol ablation may become a promising minimally invasive treatment for insulinoma because of its safety, efficacy and low price.Trail registrationClinical Trial.gov, NCT02121366Key words: Insulinoma; EUS; Alcohol injection; Efficacy" @default.
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- W3030183417 date "2016-02-20" @default.
- W3030183417 modified "2023-09-23" @default.
- W3030183417 title "Efficacy of EUS-guided ethanol ablation in the treatment of insulinoma" @default.
- W3030183417 doi "https://doi.org/10.3760/cma.j.issn.1007-5232.2016.02.002" @default.
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