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- W3030185346 abstract "The innate immunity system is the first defense line against deep fungal invasion and the pattern recognition receptors (PRRs) are considered as its critical components. Recent researches show that single nucleotide polymorphisms (SNPs) of PRRs have been discovered to play a pivotal role in host’s susceptibility to invasive fungal infection. In this article, PPRs mechanism on invasive fungal infection, polymorphisms of Toll-like receptors (TLRs) , C-type lectin receptors (CLRs) and related cytokines and their relationship with host susceptibility to invasive fungal infection are reviewed.Key words: Receptors, pattern recognition; Genetic polymorphism; Invasive fungal infection; Susceptibility" @default.
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- W3030185346 date "2015-12-25" @default.
- W3030185346 modified "2023-09-23" @default.
- W3030185346 title "Effect of genetic polymorphism of pattern recognition receptors on host susceptibility to invasive fungal infection" @default.
- W3030185346 doi "https://doi.org/10.3760/cma.j.issn.1673-4149.2015.06.011" @default.
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