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- W3030221421 abstract "ObjectiveTo investigate the effect of sleeve gastrotomy (SG) and gastric plication (GP) on the short-term metabolism in type 2 diabetes mellitus (T2DM) Zucker fatty rats.MethodsThirty healthy male rats were randomly allocated into three groups: Sham, SG and GP groups, and devices like metabolic cage were applied to detect the metabolic changes in the third week after operation.ResultsThe body weight of the SG and GP group decreased, but no statistical significance was found when compared with that of the Sham group. Less food consumption were found in SG (P<0.05) and GP (P<0.05) groups compared with that of the Sham group. In the daytime, the energy expenditure of SG group was higher than that of the sham group (P<0.01) , while in the night, the energy expenditure of both the SG (P<0.001) and GP (P<0.001) groups were higher than that of the Sham group. In the night, the activity level of SG (P<0.05) and GP (P<0.05) groups were lower than that of the Sham group, and activity level in the night was lower than that in the daytime for SG group (P<0.05) . In the daytime, the respiratory exchange rate (RER) of the SG (P<0.001) and GP (P<0.001) group were lower than that of the Sham group, and the night RER of GP group was higher than that in the daytime (P<0.05) . No statistical significance was found in terms of the average speed among the three groups. The average speed of the Sham (P<0.05) and SG (P<0.05) group in the night were faster that in the daytime. The fasting plasma glucose (FPG) of SG and GP group were improved compared with that of the Sham group.ConclusionSG and GP procedures can improve the metabolism of diabetic rats in the short term.Key words: Sleeve gastrotomy; Gastric plication; Obesity type 2 diabetes; Food consumption; Energy expenditure; Respiratory exchange rate" @default.
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- W3030221421 date "2018-12-25" @default.
- W3030221421 modified "2023-09-28" @default.
- W3030221421 title "Effect of short-term energy metabolism by which sleeve gastrotomy (SG) and gastric plication (GP) alter on obesity type 2 diabetes Zucker fatty rats" @default.
- W3030221421 doi "https://doi.org/10.3760/cma.j.issn.1674-6090.2018.06.003" @default.
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