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- W3030248888 abstract "目的探讨支气管热成形术(BT)治疗难治性哮喘患者的临床疗效。方法回顾性分析接受BT治疗的难治性哮喘患者5例(15例次)的手术情况，比较治疗前、三次手术治疗后3周及第三次手术后12周者临床症状，分析肺功能、呼出气一氧化氮(FeNO)、6 min步行距离、哮喘控制测试表(ACT)评分变化。结果5例难治性哮喘患者在病情稳定期于手术室接受BT支气管热成形手术治疗共15例次，手术过程顺利，患者耐受性好，5例次患者术后12 h内出现咳嗽加重、痰液黏稠及呼吸困难加重，程度均不重，给予拍背排痰、雾化吸入支气管扩张剂及经支气管镜取出痰痂引流后均明显好转，1例次患者手术后出现手术区域肺炎表现，经给予支气管镜取出痰痂，并抗生素治疗5 d后肺炎痊愈；5例患者术后各观察节点呼吸困难程度均较前明显改善，运动耐量提升，FeNO均逐渐下降，ACT评分增加，但肺功能无明显改善；肺部高分辨CT监测提示肺部结构无显著改变。结论BT是对难治性哮喘患者传统药物治疗无效情况下的有效补充治疗手段，能显著改善患者生活质量，患者能从每次手术后受益，同时患者耐受性好；但治疗后患者肺功能无明显改善。" @default.
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- W3030248888 date "2017-03-01" @default.
- W3030248888 modified "2023-09-23" @default.
- W3030248888 title "Clinical observation of bronchial thermoplasty in the treatment of 5 patients with refractory asthma" @default.
- W3030248888 doi "https://doi.org/10.3760/cma.j.issn.1008-6706.2017.05.035" @default.
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