FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3030255275> ?p ?o ?g. }

• W3030255275 endingPage "687" @default.
• W3030255275 startingPage "685" @default.
• W3030255275 abstract "Objective To investigate the effects of different blood pH of the recipients on ischemiareperfusion (I/R) injury to the transplanted lungs in rats. Methods Sixty-four pure bred male SD rats weighing 250-350 g were randomly divided into equal numbers of donors and recipients and the recipient rats were randomly divided into 4 groups(n = 8 each). Both donor and recipient rats were anesthetized with intraperitoneal (IP)ketamine 15 mg/kg and diazepam 6 mg/kg, tracheostomized and mechanically ventilated. In donor rats heparin 1 ml was injected via inferior vena cava and 4 ℃ LDP solution 40 ml was injected via pulmonary artery . The left lung was then removed and placed in 4℃ LDP solution and kept for 4 h. The left lung transplantation was performed using two-cuff-one-stent anastomosis technique. Before the transplanted lung was reperfused, the recipients' blood pH was adjusted to 7.4 (group Ⅰ), 7.2 (group Ⅱ), 7.3 (group Ⅲ) and 7.5 (group Ⅳ) by HCI and NaHCO3 solutions infused via femoral vein. After 2 h reperfusion, the transplants were removed for microscopic examination and determination of W/D lung weight ratio, MPO and SOD activities and MDA, TNF-α and IL-8 contents. Results SOD activity was significantly higher while MPO activity, and MDA, TNF-α and IL-8 contents in the lung tissue were significantly lower in group Ⅲ than in group Ⅰ . There was no significant difference in SOD and MPO activities and MDA, TNF-α, and IL-8 contents in the lung tissue among group Ⅰ , Ⅱ and Ⅳ. There was no significant difference in W/D lung weight ratio among the 4 groups. Microscopic examination showed that the histological damage was attenuated in group Ⅲ compared with the other 3 groups. Conclusion The I/R injury to the transplanted rat lungs can be effectively alleviated by reducing blood pH of the recipients to 7.3.Key words: Hydrogen-ion concentration;  Lung transplantation;  Reperfusion injury" @default.
• W3030255275 created "2020-06-05" @default.
• W3030255275 creator A5011065752 @default.
• W3030255275 creator A5067908272 @default.
• W3030255275 creator A5079789267 @default.
• W3030255275 date "2010-06-20" @default.
• W3030255275 modified "2023-09-27" @default.
• W3030255275 title "Effects of different blood pH of the recipients on ischemia-reperfusion injury to the transplanted lungs in rats" @default.
• W3030255275 doi "https://doi.org/10.3760/cma.j.issn.0254-1416.2010.06.016" @default.
• W3030255275 hasPublicationYear "2010" @default.
• W3030255275 type Work @default.
• W3030255275 sameAs 3030255275 @default.
• W3030255275 citedByCount "0" @default.
• W3030255275 crossrefType "journal-article" @default.
• W3030255275 hasAuthorship W3030255275A5011065752 @default.
• W3030255275 hasAuthorship W3030255275A5067908272 @default.
• W3030255275 hasAuthorship W3030255275A5079789267 @default.
• W3030255275 hasConcept C126322002 @default.
• W3030255275 hasConcept C126894567 @default.
• W3030255275 hasConcept C141071460 @default.
• W3030255275 hasConcept C2777202286 @default.
• W3030255275 hasConcept C2777714996 @default.
• W3030255275 hasConcept C2780114680 @default.
• W3030255275 hasConcept C2781448352 @default.
• W3030255275 hasConcept C2910216633 @default.
• W3030255275 hasConcept C2911091166 @default.
• W3030255275 hasConcept C2993337849 @default.
• W3030255275 hasConcept C42219234 @default.
• W3030255275 hasConcept C541997718 @default.
• W3030255275 hasConcept C71924100 @default.
• W3030255275 hasConcept C8443397 @default.
• W3030255275 hasConceptScore W3030255275C126322002 @default.
• W3030255275 hasConceptScore W3030255275C126894567 @default.
• W3030255275 hasConceptScore W3030255275C141071460 @default.
• W3030255275 hasConceptScore W3030255275C2777202286 @default.
• W3030255275 hasConceptScore W3030255275C2777714996 @default.
• W3030255275 hasConceptScore W3030255275C2780114680 @default.
• W3030255275 hasConceptScore W3030255275C2781448352 @default.
• W3030255275 hasConceptScore W3030255275C2910216633 @default.
• W3030255275 hasConceptScore W3030255275C2911091166 @default.
• W3030255275 hasConceptScore W3030255275C2993337849 @default.
• W3030255275 hasConceptScore W3030255275C42219234 @default.
• W3030255275 hasConceptScore W3030255275C541997718 @default.
• W3030255275 hasConceptScore W3030255275C71924100 @default.
• W3030255275 hasConceptScore W3030255275C8443397 @default.
• W3030255275 hasIssue "06" @default.
• W3030255275 hasLocation W30302552751 @default.
• W3030255275 hasOpenAccess W3030255275 @default.
• W3030255275 hasPrimaryLocation W30302552751 @default.
• W3030255275 hasRelatedWork W2067620482 @default.
• W3030255275 hasRelatedWork W2347224908 @default.
• W3030255275 hasRelatedWork W2357010644 @default.
• W3030255275 hasRelatedWork W2363063493 @default.
• W3030255275 hasRelatedWork W2367000314 @default.
• W3030255275 hasRelatedWork W2367701185 @default.
• W3030255275 hasRelatedWork W2369719858 @default.
• W3030255275 hasRelatedWork W2371130897 @default.
• W3030255275 hasRelatedWork W2373517359 @default.
• W3030255275 hasRelatedWork W2376072526 @default.
• W3030255275 hasRelatedWork W2377556125 @default.
• W3030255275 hasRelatedWork W2379677482 @default.
• W3030255275 hasRelatedWork W2381846903 @default.
• W3030255275 hasRelatedWork W3028652581 @default.
• W3030255275 hasRelatedWork W3029140888 @default.
• W3030255275 hasRelatedWork W3030245496 @default.
• W3030255275 hasRelatedWork W3030507984 @default.
• W3030255275 hasRelatedWork W3031019322 @default.
• W3030255275 hasRelatedWork W3032374086 @default.
• W3030255275 hasRelatedWork W3032476208 @default.
• W3030255275 hasVolume "30" @default.
• W3030255275 isParatext "false" @default.
• W3030255275 isRetracted "false" @default.
• W3030255275 magId "3030255275" @default.
• W3030255275 workType "article" @default.