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- W3030257785 abstract "目的 观察美沙拉嗪肠溶片对溃疡性结肠炎(UC)患者血清白细胞介素6(IL-6)、白细胞介素8(IL-8)的调节作用并探讨其作用机制.方法 48例UC患者随机分为两组,治疗甲组24例和治疗乙组24例.甲组采用美沙拉嗪肠溶片(惠迪)治疗,乙组采用柳氮磺胺吡啶(SASP)治疗.测定两组患者治疗前后和20例健康志愿者血清IL-6、IL-8的水平.结果 治疗甲组显效率为87%(21/24),治疗乙组显效率为62%(15/24),两组比较,差异有统计学意义(P＜0.05).甲组治疗后血清IL-6、IL-8水平与对照组比较差异无统计学意义(P＞0.05),治疗乙组治疗后血清IL-6、IL-8水平仍高于对照组(P＜0.05).结论 惠迪治疗UC疗效显著,下调IL-6、IL-8的表达及生成可能是其机制之一。" @default.
- W3030257785 created "2020-06-05" @default.
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- W3030257785 date "2006-10-28" @default.
- W3030257785 modified "2023-09-25" @default.
- W3030257785 title "美沙拉嗪对溃疡性结肠炎患者血清白细胞介素6、白细胞介素8的影响" @default.
- W3030257785 doi "https://doi.org/10.3760/cma.j.issn.1008-6706.2006.10.063" @default.
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