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- W3030273452 abstract "Objective To introduce the treatment for refractory sarcoidosis patients with methotrexate (MTX).Methods The clinical presentations,course and outcome of 3 cases of sarcoidosis treated with MTX were reported.Literatures concering MTX treatment sarcoidosiswas reviewed,Results All of 3 patients had lungs and extrathoracic involved.Two patients were improved with initially treatment with prednisone,but deteriorated while prednisone is tapered.They made progress when MTX was added.One patient misused MTX and was crued with prednisone.In those patients,two suffered fromgastro-intestinal symptom and hepatotoxicity with MTX.One passed away for severe infection.Conclusions MTX could be used to patients with refractory disease and those who have to take long-term high dose of prednisone.Side effects should be warned when MTX used.Key words: Sarcoidosis; Methotrexate; Side effect" @default.
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- W3030273452 date "2012-11-05" @default.
- W3030273452 modified "2023-09-23" @default.
- W3030273452 title "Methotrexate treatment of sarcoidosis:three cases report and review of literature" @default.
- W3030273452 doi "https://doi.org/10.3760/cma.j.issn.1673-436x.2012.021.010" @default.
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