FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3030351132> ?p ?o ?g. }

• W3030351132 endingPage "155" @default.
• W3030351132 startingPage "150" @default.
• W3030351132 abstract "ObjectiveTo find a new method for evaluating the left ventricular relaxation time constant Tau with aortic regurgitation by continuous wave Doppler.MethodsTwelve Beagle dogs were included in the study. The dog aortic regurgitation model was produced under ultrasound guiding by carotid artery puncture. Aortic pressure was measured by pressure catheter and left ventricular pressure was measured by Millar catheter which was introduced into the left ventricular through cardiac apex. Then microspheres were injected into the left coronary artery under the guidance of ultrasound to induce acute ischemic left ventricular dysfunction, when left ventricular end-diastolic pressure increased more than 5 mmHg (1 mmHg=0.133 kPa). Dobutamine or esmolol was infused to alter left ventricular function. Aortic regurgitation velocity spectrum was recorded by the continuous-wave Doppler echocardiography in different hemodynamic status. At the same time, left ventricular pressure, dp/dt, aortic pressure and continuous ECG tracing were displayed on the multi-channel physiological recorder. Measurement was recorded of –dp/dtmax in the dp/dt tracings and the pressure at the time of –dp/dtmax in the left ventricular pressure tracings. Tau =-P/(dp/dtmax), Tau was the catheter-derived time constant (Taucatheter). Aortic regurgitation spectrum of original audio data was post-processed with MATLAB mathematical software. The spectral lines refresh time of about 300 μs was chosen to form a new Doppler spectrum. Three points: (t1,1 m/s), (t2, 2 m/s) and (t3, 3 m/s) were selected in aortic regurgitation velocity spectrum and t1, t2 and t3 was put into the corresponding Tau formula: Tau=(t2-t1)/ln[(ADP-C-4)/(ADP-C-16)], Tau=(t3-t1)/ln[(ADP-C-4)/(ADP-C-36)]. Tau was the aortic regurgitant time constant (Tauultrasound). The difference between Taucatheter and Tauultrasound was compared by paired t test. The correlation between Taucatheter and Tauultrasound was analyzed by Pearson correlation analysis.ResultsTwelve dogs were successfully produced aortic regurgitation model. Two dogs died of ventricular fibrillation during the procedure of acute ischemic left ventricular diastolic dysfunction. The range of the Taucatheter was between 27.12 ms and 86.88 ms with an average of (48.973±14.667) ms; the range of the Tauultrasound was between 28.13 ms and 90.18 ms with an average of (51.236±15.146) ms. The difference was not statistically significant (t=1.841, P>0.05). Pearson correlation analysis showed that Taucatheter was positively correlated with Tauultrasound (r=0.89, P=0.000).ConclusionChoosing three points: (t1, 1 m/s), (t2, 2 m/s) and (t3, 3 m/s) in aortic regurgitant velocity spectrum and putting into the corresponding formula, we can calculate Tau, which had a good correlation with the catheter-derived Tau.Key words: Left ventricular relaxation time constant;  Continuous wave Doppler; Aortic valve insufficiency" @default.
• W3030351132 created "2020-06-05" @default.
• W3030351132 creator A5020383114 @default.
• W3030351132 creator A5024723836 @default.
• W3030351132 creator A5045968229 @default.
• W3030351132 creator A5058673686 @default.
• W3030351132 creator A5090321957 @default.
• W3030351132 date "2017-01-01" @default.
• W3030351132 modified "2023-10-03" @default.
• W3030351132 title "Calculation of left ventricular relaxation time constant Tau in dogs with aortic regurgitation by continuous wave Doppler" @default.
• W3030351132 doi "https://doi.org/10.3877/cma.j.issn.1672-6448.2017.01.016" @default.
• W3030351132 hasPublicationYear "2017" @default.
• W3030351132 type Work @default.
• W3030351132 sameAs 3030351132 @default.
• W3030351132 citedByCount "0" @default.
• W3030351132 crossrefType "journal-article" @default.
• W3030351132 hasAuthorship W3030351132A5020383114 @default.
• W3030351132 hasAuthorship W3030351132A5024723836 @default.
• W3030351132 hasAuthorship W3030351132A5045968229 @default.
• W3030351132 hasAuthorship W3030351132A5058673686 @default.
• W3030351132 hasAuthorship W3030351132A5090321957 @default.
• W3030351132 hasConcept C126322002 @default.
• W3030351132 hasConcept C164705383 @default.
• W3030351132 hasConcept C178853913 @default.
• W3030351132 hasConcept C26635844 @default.
• W3030351132 hasConcept C2780168065 @default.
• W3030351132 hasConcept C2781185063 @default.
• W3030351132 hasConcept C39124391 @default.
• W3030351132 hasConcept C71924100 @default.
• W3030351132 hasConceptScore W3030351132C126322002 @default.
• W3030351132 hasConceptScore W3030351132C164705383 @default.
• W3030351132 hasConceptScore W3030351132C178853913 @default.
• W3030351132 hasConceptScore W3030351132C26635844 @default.
• W3030351132 hasConceptScore W3030351132C2780168065 @default.
• W3030351132 hasConceptScore W3030351132C2781185063 @default.
• W3030351132 hasConceptScore W3030351132C39124391 @default.
• W3030351132 hasConceptScore W3030351132C71924100 @default.
• W3030351132 hasIssue "1" @default.
• W3030351132 hasLocation W30303511321 @default.
• W3030351132 hasOpenAccess W3030351132 @default.
• W3030351132 hasPrimaryLocation W30303511321 @default.
• W3030351132 hasRelatedWork W147361957 @default.
• W3030351132 hasRelatedWork W1970348011 @default.
• W3030351132 hasRelatedWork W1989879970 @default.
• W3030351132 hasRelatedWork W1992682467 @default.
• W3030351132 hasRelatedWork W2003670885 @default.
• W3030351132 hasRelatedWork W2005978587 @default.
• W3030351132 hasRelatedWork W2025539610 @default.
• W3030351132 hasRelatedWork W2087681046 @default.
• W3030351132 hasRelatedWork W2166387952 @default.
• W3030351132 hasRelatedWork W2344312528 @default.
• W3030351132 hasRelatedWork W2348154674 @default.
• W3030351132 hasRelatedWork W2358974528 @default.
• W3030351132 hasRelatedWork W2361358610 @default.
• W3030351132 hasRelatedWork W2409567719 @default.
• W3030351132 hasRelatedWork W2427936884 @default.
• W3030351132 hasRelatedWork W2435969230 @default.
• W3030351132 hasRelatedWork W2471354029 @default.
• W3030351132 hasRelatedWork W2802113685 @default.
• W3030351132 hasRelatedWork W3132200534 @default.
• W3030351132 hasRelatedWork W3140394255 @default.
• W3030351132 hasVolume "14" @default.
• W3030351132 isParatext "false" @default.
• W3030351132 isRetracted "false" @default.
• W3030351132 magId "3030351132" @default.
• W3030351132 workType "article" @default.