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- W3030355001 abstract "Neoadjuvant chemoradiotherapy (nCRT) and subsequent radical resection have become the standard care of locally advanced rectal cancer (LARC). However, conventional radical is associated with high intra- and post-operative morbidities, and a temporary or permanent stoma in some cases, impaired sexual and urinary function, and it eventually impair the quality of life. Rectum-preserving surgery is a novel concept in the era of nCRT, which will maximally benefit patients through the minimized injuries. This strategy has been increasingly utilized in LARC following nCRT. Nevertheless, it lacks high-level evidence of evidence-based medicine, and the long-term oncological safety remains to be determined by larger, multicenter, randomized clinical trials. The crucial aspect of rectum-preserving surgery is to accurately evaluate the status of primary tumor and metastatic lymph nodes, and thus to selective patients who could benefit from this strategy most.Key words: Rectal neoplasms; Neoadjuvant chemoradiotherapy; Organ preserving" @default.
- W3030355001 created "2020-06-05" @default.
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- W3030355001 date "2017-07-20" @default.
- W3030355001 modified "2023-09-25" @default.
- W3030355001 title "Rectum-preserving surgery in the era of neoadjuvant chemoradiotherapy" @default.
- W3030355001 doi "https://doi.org/10.3760/cma.j.issn.1673-9752.2017.07.005" @default.
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