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- W3030383775 abstract "ObjectiveTo discuss the clinical application value of modified purse-string suture in cervical wound after cold knife conization (CKC).MethodsMedical records of 291 patients who received CKC treatment of cervical intraepithelial neoplasia (CIN)Ⅱ-Ⅲ in Department of Gynecology and obstetrics, First People's Hospital of Yangtze University from January 2009 to December 2013 were included into this study. They were divided into modified group (n=161) and control group (n=130) according to two different suture methods. A total of 161 cases with modified purse-string suture from January 2012 to December 2013 were included into modified group, and another 130 cases with traditional Sturmdorf suture from January 2009 to December 2011 were included into control group. Operation time, hospitalization, intraoperative and postoperative blood loss, postoperative histopathological examination results, postoperative cervical plastic satisfaction, postoperative fever and postoperative follow-up of 3 months between two groups were compared. There were no statistically significant differences bwteen two groups in the aspects of age, gravidity, parity and the proportion of menopause (P>0.05). The study protocol was approved by the Ethical Review Board of Investigation in Human Being of First People's Hospital of Yangtze University.Results①The operation time of modified group and control group were (28.2±7.9) min and (40.5±9.4) min, respectively, which had statistically significant difference (t=12.127, P 0.05). ② The average intraoperative blood loss of modified group was (38.6±24.3) mL and control group was (67.0±18.6) mL, and the difference was statistically significant (t=10.978, P 0.05). ③There were no significant differences between two groups in the histopathological examination results (the incidence rates of pathological upgrade, invasive cervical cancer detection and positive surgical margin)(P>0.05). ④ There were significant differences between two groups in postoperative cervical shape satisfaction (χ2=14.883, 8.432, 7.587; P 0.05). ⑥After 3 months follow-up, the incidence rates of cervical granulation and cervical adhesion of modified group were significant lower than those of control group, which had significant differences (χ2=4.638, 3.754; P 0.05).ConclusionsThe modified purse-string suture presents effective hemostasis in CKC, leading to simple operation, short operation time, less blood loss and shorter postoperative hospitalization.Key words: Cervical intraepithelial neoplasia; Cold knife conization; Suture techniques; Women" @default.
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- W3030383775 date "2016-02-01" @default.
- W3030383775 modified "2023-09-28" @default.
- W3030383775 title "Application value of modified purse-string suture in cold knife conization" @default.
- W3030383775 doi "https://doi.org/10.3877/cma.j.issn.1673-5250.2016.01.014" @default.
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