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- W3030392359 abstract "ObjectiveTo analyze the time of removing setons by observing 30 cases of the infliximab (IFX) combined drainage setons therapy in the treatment of perianal fistulising Crohn′s disease.MethodsThirty patients of perianal fistulising Crohn′s disease of Department of Colorectal Surgery, Jiangsu Prorince Hospital of TCM in Aug. 2015 to Jul. 2017 were treated with drainage setons followed by intravenous IFX injections according to the standard, and setons were removed after the third injection of IFX.The method of repeated measurement were adopted to record. Clinical symptoms, perianal manifestations, laboratory indexes, healing rate and general linear model and nonparametric test of SPSS 23.0 software were used for statistical analysis.ResultsThe differences of WBC, CRP, ESR, HB, PLT, BMI, CDAI and PDAI between post treatment and pretreatment were statistically significant (P 0.05) at the 14th week, 22th week and 30th week.ConclusionIFX combined drainage setons which was removed when the induction therapy finished can induce Crohn′s disease remission, improve laboratory index and promote fistula closure. the clinical efficacy in short time was stable.Key words: Rectal fistula; Treatment outcome; Drainage; Crohn′s disease; Infliximab; Seton" @default.
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- W3030392359 date "2018-08-15" @default.
- W3030392359 modified "2023-09-22" @default.
- W3030392359 title "Rapeutic evaluation of 30 cases of perianal fistulising Crohn′s disease who were removed setons at fixed time" @default.
- W3030392359 doi "https://doi.org/10.3760/cma.j.issn.1673-4203.2018.08.010" @default.
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