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- W3030442333 abstract "4E-BP1 is the specific inhibitor of eukaryotic initiation factor 4E, recent studies have shown, phosphorylated 4E-binding protein 1(P-4E-BP1)overexpression has been observed in a variety of human cancers, including breast cancer, cervical cancer, thyroid cancer, prostate cancer, colorectal cancer, et al. Its expression level is associated with tumor size, invasion, metastasis, prognosis and other clinical and pathological features. Thus evaluate P-4E-BP1 expression level which is associated with tumor biological behavior will help us better understand the etiology, development, invasion and metastasis mechanisms of cancer.Moreover, P-4E-BP1 may become a new target for cancer treatment and provide new ideas for the clinical cancer treatment.Key words: 4E-BP1 ; Phosphorylation; Cancer" @default.
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- W3030442333 date "2011-09-05" @default.
- W3030442333 modified "2023-09-22" @default.
- W3030442333 title "Phosphorylated 4E-binding protein 1 overexpression in human cancer" @default.
- W3030442333 doi "https://doi.org/10.3760/cma.j.issn.1673-4394.2011.05.004" @default.
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