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- W3030463007 abstract "Objective To research the degression of renal function of 99Tcm-diethylene triamine pentaaceticacid (99Tcm-DTPA) renal imaging in rabbits with acute upper urinary tract obstruction and its early recovery after relief. Methods Twenty-four health rabbit models with left acute upper urinary tract obstruction were built up. 99Tcm-DTPA renal imaging was performed before making model and after obstruction 1, 3, 5-7 and more than 8 weeks respectively and 4 weeks after relief of obstruction. Results After obstnrction 1 and 3 weeks, 99Tcm-DTPA imaging showed development in left renal. Values of glomerular filtration rate (GFR) and uptake ratio decreased, while time to reach the peak increased. These are obviusly different compared with those before obstruction (t=2.916, t=7.034, P 0.05). With obstruction of 5-7 weeks, the GRF and uptake ratio, could recover partly to some extent. But with obstruction for more than 8 weeks, the renal function could not recover. Conclusions For the acute upper urinary tract obstruction, the renal function is most remarkable decreased in the early time, and can be restored after relief. For long time obstruction, even if relieved, the renal function is not easily to restore. The dynamic renal imaging can reflect the extent of the renal damage and its recovery, and could be used as a reliable indicator.Key words: Technetium Tc 99m pentetate; Urethral obstruction; Glomerular filtration rate; Renal dynamic imaging; Rabbits" @default.
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- W3030463007 date "2008-11-25" @default.
- W3030463007 modified "2023-09-24" @default.
- W3030463007 title "The value of dynamic renal 99 Tc m -diethylene triamine penta acetic acid imaging in rabbits with acute upper urinary tract obstruction" @default.
- W3030463007 doi "https://doi.org/10.3760/cma.j.issn.1673-4114.2008.06.007" @default.
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