Matches in SemOpenAlex for { <https://semopenalex.org/work/W3030470829> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W3030470829 endingPage "1186" @default.
- W3030470829 startingPage "1183" @default.
- W3030470829 abstract "Objective To investigate the incidence and relevant factors of upper gastrointestinal bleeding(UGB)in patients with coronary heart disease(CHD)undergoing dual antiplatelet therapy(DAT)with aspirin plus clopidogrel.Methods A total of 391 CHD patients treated with aspirin plus clopidogrel (DAT group)and 502 control CHD patients receiving single antiplatelet therapy(SAT)with aspirin or clopidogrel(SAT group)were enrolled.The incidence and relevant factors associated with UGB were retrospectively analyzed in both groups of patients.Data were analyzed with Chi-square test and logistic regression by using SAS software version 9.0.Results The incidence of UGB in DAT group was significantly higher compared with SAT group(7.1％ vs.3.4％,P ＜ 0.01).The factors,including DAT,age over 65 years,medication duration over 3 months and previous digestive diseases increased the risk of UGB in CHD patients(P ＜ 0.05),while the use of PPIs(proton-pump inhibitors)or gastric mucosal protectives lowered the risk of UGB(OR:0.415,95％ CI 0.226 ～ 0.762,P =0.0035).Conclusions DAT can significantly increase the risk of UGB.UGB can be increased in elderly CHD patients and those with long-term medication and previous digestive diseases.Utility of PPIs or gastric mucosal protectives can effectively lower the incidence of UGB.Key words: Antiplatelet therapy; Aspirin; Clopidogrel; Upper gastrointestinal bleeding" @default.
- W3030470829 created "2020-06-05" @default.
- W3030470829 creator A5026702753 @default.
- W3030470829 creator A5059959987 @default.
- W3030470829 date "2011-11-10" @default.
- W3030470829 modified "2023-09-25" @default.
- W3030470829 title "Incidence of upper gastrointestinal bleeding and relevant factors associated with dual antiplatelet therapy in patients with coronary heart disease" @default.
- W3030470829 doi "https://doi.org/10.3760/cma.j.issn.1671-0282.2011.11.018" @default.
- W3030470829 hasPublicationYear "2011" @default.
- W3030470829 type Work @default.
- W3030470829 sameAs 3030470829 @default.
- W3030470829 citedByCount "0" @default.
- W3030470829 crossrefType "journal-article" @default.
- W3030470829 hasAuthorship W3030470829A5026702753 @default.
- W3030470829 hasAuthorship W3030470829A5059959987 @default.
- W3030470829 hasConcept C120665830 @default.
- W3030470829 hasConcept C121332964 @default.
- W3030470829 hasConcept C126322002 @default.
- W3030470829 hasConcept C151956035 @default.
- W3030470829 hasConcept C2776345487 @default.
- W3030470829 hasConcept C2777628954 @default.
- W3030470829 hasConcept C2777849778 @default.
- W3030470829 hasConcept C2778080469 @default.
- W3030470829 hasConcept C2778451229 @default.
- W3030470829 hasConcept C2781025758 @default.
- W3030470829 hasConcept C61511704 @default.
- W3030470829 hasConcept C71924100 @default.
- W3030470829 hasConcept C90924648 @default.
- W3030470829 hasConceptScore W3030470829C120665830 @default.
- W3030470829 hasConceptScore W3030470829C121332964 @default.
- W3030470829 hasConceptScore W3030470829C126322002 @default.
- W3030470829 hasConceptScore W3030470829C151956035 @default.
- W3030470829 hasConceptScore W3030470829C2776345487 @default.
- W3030470829 hasConceptScore W3030470829C2777628954 @default.
- W3030470829 hasConceptScore W3030470829C2777849778 @default.
- W3030470829 hasConceptScore W3030470829C2778080469 @default.
- W3030470829 hasConceptScore W3030470829C2778451229 @default.
- W3030470829 hasConceptScore W3030470829C2781025758 @default.
- W3030470829 hasConceptScore W3030470829C61511704 @default.
- W3030470829 hasConceptScore W3030470829C71924100 @default.
- W3030470829 hasConceptScore W3030470829C90924648 @default.
- W3030470829 hasIssue "11" @default.
- W3030470829 hasLocation W30304708291 @default.
- W3030470829 hasOpenAccess W3030470829 @default.
- W3030470829 hasPrimaryLocation W30304708291 @default.
- W3030470829 hasRelatedWork W1495846107 @default.
- W3030470829 hasRelatedWork W1546638812 @default.
- W3030470829 hasRelatedWork W2022037434 @default.
- W3030470829 hasRelatedWork W2038695648 @default.
- W3030470829 hasRelatedWork W2045384387 @default.
- W3030470829 hasRelatedWork W2047873054 @default.
- W3030470829 hasRelatedWork W2071508828 @default.
- W3030470829 hasRelatedWork W2084280109 @default.
- W3030470829 hasRelatedWork W2138619261 @default.
- W3030470829 hasRelatedWork W2164760312 @default.
- W3030470829 hasRelatedWork W2282589332 @default.
- W3030470829 hasRelatedWork W2311450563 @default.
- W3030470829 hasRelatedWork W2358329200 @default.
- W3030470829 hasRelatedWork W2501371925 @default.
- W3030470829 hasRelatedWork W2607698451 @default.
- W3030470829 hasRelatedWork W2768141719 @default.
- W3030470829 hasRelatedWork W3049538636 @default.
- W3030470829 hasRelatedWork W3092176464 @default.
- W3030470829 hasRelatedWork W3108340099 @default.
- W3030470829 hasRelatedWork W2589502213 @default.
- W3030470829 hasVolume "20" @default.
- W3030470829 isParatext "false" @default.
- W3030470829 isRetracted "false" @default.
- W3030470829 magId "3030470829" @default.
- W3030470829 workType "article" @default.