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- W3030485873 abstract "目的观察大鼠睡眠剥夺后相关脑区5-HT受体亚型的表达情况,探讨大鼠睡眠的5-HT机制.方法以大平台作为对照组,采用小平台水环境法对大鼠进行睡眠剥夺,根据5-HT1A和5-HT2A受体互补DNA序列合成相应的特异性引物,用PCR法观察大鼠睡眠剥夺后海马、下丘脑和中脑5-HT1A和5-HT2A受体表达.结果大鼠睡眠剥夺后海马和中脑5-HT1A受体表达增强,与对照组比较有显著性差异(P<0.01～0.05),下丘脑无明显变化.实验组和对照组各脑区5-HT2A受体无明显变化.结论 5-HT1A与大鼠的睡眠调节有关." @default.
- W3030485873 created "2020-06-05" @default.
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- W3030485873 date "2002-07-20" @default.
- W3030485873 modified "2023-10-18" @default.
- W3030485873 title "Effect of sleep deprivation on the expression of 5-HT receptor subtypes in rat brain" @default.
- W3030485873 doi "https://doi.org/10.3760/cma.j.issn.1674-6554.2002.04.002" @default.
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