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- W3030486730 abstract "Objective To investigate the dynamic changes and significance of serum cytokines in patients with dif-ferent prognosis after cardiopulmonary resuscitated. Methods The patients undergone CPR were divided into recovers the successful group and anabiesis defeat group. The levels of serum tumor necrosisfactor - α (TNF - α), interleukin - 4 (IL - 4), interleukin - 8 (IL - 8), interleukin - 10 (IL - 10) were measured in 27 patients after CPR with return of spontane-ous circulation(ROSC) by enzyme- linked immunosorbent assay(ELISA). Results In group B,the levels of serum tumor necrosisfactor-α(TNF-α) was increased and significantly higher shah group A1> and A2> at cardiac arrest- before CPR (P > 0.05). There no significant difference of the serum IL-4,IL-8,IL- 10 among the three groups. After group A1> re-covets the MODS disease incidence rate to be higher than group A2> (14/19,2/8, P (P ,level of IL -4 and IL - 10 were higher than when its CPR (P (P >0.05), level of ROSC 72 h TNF-α decrease, IL-4 was higher than group A2. Conclusions The serum eytokines play an important role in the pathogenesis of lacks the blood - to pour into a-gain after. To intervene and maintain the balance of cytokines may be a way to improve the patients prognosis after CPR. Key words: Heart arrest; Cardiopulmonary resuscitation; Cytokines; Prognosis ; ELISA" @default.
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- W3030486730 date "2009-08-10" @default.
- W3030486730 modified "2023-09-22" @default.
- W3030486730 title "Dynamic changes and significance of serum cytokines in patients with different prognosis after cardiopulmonary resuscitated" @default.
- W3030486730 doi "https://doi.org/10.3760/cma.j.issn.1674-4756.2009.15.004" @default.
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