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- W3030508220 abstract "BackgroundThe early growth response gene-1(Egr-1) is considered to be a triggering mechanism that maintains long term potentiation and activates neurogenesis. The expression of Egr-1 protein is closely associated with the consolidation, reconsolidation and extinction of long term memory.ObjectiveProviding potential research targets for studying the mechanism and treatment of postoperative cognitive dysfunction.ContentWe review the structure, expression pattern of Egr-1 protein and its roles in learning and memory.TrendEgr-1 plays different roles in different phases of memory, but the specific signaling pathways and their relationship with postoperative cognitive dysfunction deserve further clarification.Key words: The early growth response gene-1; Signal pathway; Learning and memory" @default.
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- W3030508220 date "2017-05-15" @default.
- W3030508220 modified "2023-09-28" @default.
- W3030508220 title "The role of the early growth response gene-1 in learning and memory process" @default.
- W3030508220 doi "https://doi.org/10.3760/cma.j.issn.1673-4378.2017.05.018" @default.
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