Matches in SemOpenAlex for { <https://semopenalex.org/work/W3030519703> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W3030519703 endingPage "456" @default.
- W3030519703 startingPage "452" @default.
- W3030519703 abstract "Objective To investigate the change of dendritic cells (DCs) in rats with hepatic carcinoma treated by radiofrequency ablation (RFA),and to explore the mechanisms of anti-tumor immune response to RFA. Methods Forty healthy SD rats with established animal model of hepatic carcinoma were randomly divided into control group (n = 10) ,RFA 7 d group (n = 16) and RFA 14 d group (n = 14). The rats of control group were killed without treatment. The other rats were killed in 7 d and 14 d after RFA treatment respectively. Peripheral blood, liver tissue around the ablation area and spleen were taken out. The OX62,OX6,CD86 of DCs were analyzed with flowcytometry. Results ①OX62 cells accounted for (0.45 ± 0.19)% of mononuelear cells in peripheral blood in control group. The account of OX62 cells increased to (0.78 ± 0.30)% and (1.53 % 0.80)% in RFA 7 d and 14 d groups respectively. There were significant differences between control and RFA 7 d group, control and RFA 14 d group (P<0.05). ②OX62 cells accounted for (18.91 ± 4.58)% of mononuclear cells in liver tissue around the tumor in control group. The account of OX62 cells increased to (24.49 ± 4.59)% in RFA 7 d group (P<0.05). The expression of OX6 on DCs in liver tissue was (15.29 ± 4.59)% and increased to (34.2 ± 11.62)% and (39.18 ± 9.14)% in RFA 7 d and RFA 14 d group respectively (P<0.05). ③OX62 cells accounted for (11.69 ± 4.39)% of mononuclear cells in spleen in control group which increased to (15.10±2.37)% in RFA 14 d group (P<0.05). Conclusions The precursor DCs in peripheral blood and DCs in liver and spleen increased significantly after RFA. The expressions of OX6 on DCs in liver and spleen increased after RFA. RFA can promote the differentiation and maturation of DC. The increased function of antigen presenting may contribute to the anti-tumor responses after RFA.Key words: Catheter ablation; Liver neoplasms,experimental; Dendritic cells" @default.
- W3030519703 created "2020-06-05" @default.
- W3030519703 creator A5028924208 @default.
- W3030519703 creator A5033101267 @default.
- W3030519703 creator A5036399590 @default.
- W3030519703 creator A5057124541 @default.
- W3030519703 creator A5082320448 @default.
- W3030519703 date "2009-05-25" @default.
- W3030519703 modified "2023-09-23" @default.
- W3030519703 title "Influence of radiofrequency ablation on dendritic cells in rats with liver carcinoma" @default.
- W3030519703 doi "https://doi.org/10.3760/cma.j.issn.1004-4477.2009.05.029" @default.
- W3030519703 hasPublicationYear "2009" @default.
- W3030519703 type Work @default.
- W3030519703 sameAs 3030519703 @default.
- W3030519703 citedByCount "0" @default.
- W3030519703 crossrefType "journal-article" @default.
- W3030519703 hasAuthorship W3030519703A5028924208 @default.
- W3030519703 hasAuthorship W3030519703A5033101267 @default.
- W3030519703 hasAuthorship W3030519703A5036399590 @default.
- W3030519703 hasAuthorship W3030519703A5057124541 @default.
- W3030519703 hasAuthorship W3030519703A5082320448 @default.
- W3030519703 hasConcept C126322002 @default.
- W3030519703 hasConcept C126894567 @default.
- W3030519703 hasConcept C137061746 @default.
- W3030519703 hasConcept C142724271 @default.
- W3030519703 hasConcept C185592680 @default.
- W3030519703 hasConcept C202751555 @default.
- W3030519703 hasConcept C203014093 @default.
- W3030519703 hasConcept C2776231280 @default.
- W3030519703 hasConcept C2777377203 @default.
- W3030519703 hasConcept C2778019345 @default.
- W3030519703 hasConcept C2778902805 @default.
- W3030519703 hasConcept C2780931953 @default.
- W3030519703 hasConcept C3017910909 @default.
- W3030519703 hasConcept C55493867 @default.
- W3030519703 hasConcept C71924100 @default.
- W3030519703 hasConcept C8891405 @default.
- W3030519703 hasConcept C90924648 @default.
- W3030519703 hasConceptScore W3030519703C126322002 @default.
- W3030519703 hasConceptScore W3030519703C126894567 @default.
- W3030519703 hasConceptScore W3030519703C137061746 @default.
- W3030519703 hasConceptScore W3030519703C142724271 @default.
- W3030519703 hasConceptScore W3030519703C185592680 @default.
- W3030519703 hasConceptScore W3030519703C202751555 @default.
- W3030519703 hasConceptScore W3030519703C203014093 @default.
- W3030519703 hasConceptScore W3030519703C2776231280 @default.
- W3030519703 hasConceptScore W3030519703C2777377203 @default.
- W3030519703 hasConceptScore W3030519703C2778019345 @default.
- W3030519703 hasConceptScore W3030519703C2778902805 @default.
- W3030519703 hasConceptScore W3030519703C2780931953 @default.
- W3030519703 hasConceptScore W3030519703C3017910909 @default.
- W3030519703 hasConceptScore W3030519703C55493867 @default.
- W3030519703 hasConceptScore W3030519703C71924100 @default.
- W3030519703 hasConceptScore W3030519703C8891405 @default.
- W3030519703 hasConceptScore W3030519703C90924648 @default.
- W3030519703 hasIssue "05" @default.
- W3030519703 hasLocation W30305197031 @default.
- W3030519703 hasOpenAccess W3030519703 @default.
- W3030519703 hasPrimaryLocation W30305197031 @default.
- W3030519703 hasRelatedWork W1704005375 @default.
- W3030519703 hasRelatedWork W1864906020 @default.
- W3030519703 hasRelatedWork W1990730061 @default.
- W3030519703 hasRelatedWork W2023995407 @default.
- W3030519703 hasRelatedWork W2039151430 @default.
- W3030519703 hasRelatedWork W2123541316 @default.
- W3030519703 hasRelatedWork W2157974305 @default.
- W3030519703 hasRelatedWork W2348049023 @default.
- W3030519703 hasRelatedWork W2348357854 @default.
- W3030519703 hasRelatedWork W2362282004 @default.
- W3030519703 hasRelatedWork W2370750936 @default.
- W3030519703 hasRelatedWork W2375518972 @default.
- W3030519703 hasRelatedWork W2378281648 @default.
- W3030519703 hasRelatedWork W2383870604 @default.
- W3030519703 hasRelatedWork W2398677039 @default.
- W3030519703 hasRelatedWork W2408552251 @default.
- W3030519703 hasRelatedWork W2890120808 @default.
- W3030519703 hasRelatedWork W3034505780 @default.
- W3030519703 hasRelatedWork W3098958981 @default.
- W3030519703 hasRelatedWork W337904036 @default.
- W3030519703 hasVolume "18" @default.
- W3030519703 isParatext "false" @default.
- W3030519703 isRetracted "false" @default.
- W3030519703 magId "3030519703" @default.
- W3030519703 workType "article" @default.