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- W3030525191 abstract "目的 利用共焦显微镜观察比较准分子激光原位角膜磨镶术(laser in situ keratomileusis,LASIK)与准分子激光双面角膜磨镶术(both-sides LASIK,BSL)后角膜上皮下神经纤维的再生情况.方法 观察在我院行LASIK或BSL手术的患者21例(38眼),其中,LASIK组11例(22眼),BSL组10例(16眼).手术患者分别在术后1 d、1周、1个月、3个月、6个月时行角膜其焦显微镜检查,比较两组患者术后角膜上皮下神经纤维再生的情况.结果 术后1 d,角膜神经纤维多表现为长的、残留变性神经纤维与被切断的、短的、不连续的神经纤维同时存在;术后1周,两组患者角膜再生神经纤维的长度表现以≤50im或无神经纤维为主;自术后1个月起,就可见有长度>200 im的再生神经纤维出现,且随着时间延长,所占比例逐渐增加.在术后1个月、3个月、6个月,LASIK组与BSL组角膜上皮下再生神经纤维达到200im的比例分别为36.3%和12.5%,36.4%和25%,63.6%和68.8%,两组间差异没有统计学意义(P均>0.05).结论 虽然在等效球镜度、术前及术后角膜厚度、手术切削深度等方面,两组之间差异存在统计学意义,但LASIK组与BSL组术后角膜上皮下神经纤维再生长度和形态学在各时间点差异无统计学意义。" @default.
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- W3030525191 date "2008-07-31" @default.
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- W3030525191 title "The use of confocal microscopy to study the characteristics of corneal nerve regeneration after different excimer laser operations" @default.
- W3030525191 doi "https://doi.org/10.3760/cma.j.issn.1008-1801.2008.04.021" @default.
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