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- W3030540079 abstract "目的: 分析化疗方案、肿瘤临床分期对化疗毒副作用的影响.方法: 各类小儿恶性实体肿瘤85例, 化疗方案为改良CCSG、OPEC、L、DD、CYVADIC、VAC、PVB、PCV、 VAD、IRS-Ⅲ、ICE+A及Rosen方案等.以美国东部肿瘤协作组(ECOG)毒性分度标准进行毒性分析.结果: 81例出现了毒性反应, 占95.3%, 其中出现严重毒性反应27例, 占31.8%; 毒性反应出现时间平均为17.9±17.3周; 含有阿霉素、博莱霉素的方案以及长期化疗,较易引起重度毒性反应; 临床分期对化疗的毒性耐受亦有影响; 血液系统与消化系统最常受累. 结论: 化疗以达到3度以下的毒性反应为好, 应根据患儿的反应调整剂量, 做到化疗的个体化.化疗监测可以血常规和消化道反应为指标." @default.
- W3030540079 created "2020-06-05" @default.
- W3030540079 creator A5048678366 @default.
- W3030540079 date "1998-01-15" @default.
- W3030540079 modified "2023-09-23" @default.
- W3030540079 title "Adverse Effects of Chemotherapy in Children with Malignant Solid Tumors" @default.
- W3030540079 doi "https://doi.org/10.3760/cma.j.issn.0253-3006.1998.01.003" @default.
- W3030540079 hasPublicationYear "1998" @default.
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