Matches in SemOpenAlex for { <https://semopenalex.org/work/W3030551035> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W3030551035 endingPage "512" @default.
- W3030551035 startingPage "509" @default.
- W3030551035 abstract "Objective To investigate the effects of pregabalin on the postoperative analgesia in patients with lower abdominal surgery. Methods The patients aged 19-70,ASA Ⅰ -Ⅱ,scheduled for lower abdominal surgery were randomly divided into 2 groups (n=15):Group P (pregabalin) and Group C(control).The patients in Group P and C orally took pregabalin (75 mg) or self-made flour capsule 30 min prior to general anesthesia,respectively.General anesthesia was routinely induced and maintained with remifentanil,propofol and muscle relaxant.Patient-controlled intravenous analgesia (PCIA) was used in every patient.The rest pain and cough pain was assessed using vision analogue scale (VAS) at 2,4,8,12,20 h and 24 h after surgery,respectively.The effective and total numbers of PCIA,analgesic comsumption and side-effects were recorded in postoperative 24 h.Results All 30 patients completed the trial.Compared with postoperative 2 h postoperative 4,8,12,20,24 h,the PCIA effective frequency and the total number of difference was statistically significant(P＜0.05 ),Compared with group C[(6.3±0.7),(5.8±0.6),(4.9±0.5),(4.3±0.6),(2.5±0.7),(1.9±0.3)and(8.1±0.5),(7.7±0.5),(7.0±0.4),(6.3±0.6),(4.5±0.6),(3.9±0.5)],VAS during rest [(5.3±0.5),(4.5±0.6),(3.7±0.6),(2.5±0.8),(1.4±0.5),(0.8±0.4)] and cough[(7.3±0.6),(6.5±0.7),(5.5±0.5),(4.6±0.8),(3.3±0.5),(2.9±0.4) ]at each time point postoperation were lower(P＜0.05 ).Postoperative effective frequency[(2.0±0.4),(3.3±0.7),(3.9±1.1),(3.9±1.1),(3.9±1.1),(3.9±1.1)]and the total number[(2.5±0).7),(3.9±1.0),(4.5±1.4),(4.5±1.4),(4.5±1.4),(4.5±1.4)] of PCIA were lower in group P than that in group C(P＜0.05).Only nausea and vomiting were observed as post operation side effects,and there was no significant difference between the two groups(P＞0.05). Conclusions Orally-taken pregabalin(75 mg) prior to anesthesia may improve the treatment of postoperative analgesia,reduce the consumption of analgestics with less sideeffects and contribute to the patients'recovery.Key words: Pregabalin; Analgesia; Patient-control" @default.
- W3030551035 created "2020-06-05" @default.
- W3030551035 creator A5041373689 @default.
- W3030551035 creator A5060120199 @default.
- W3030551035 date "2012-08-15" @default.
- W3030551035 modified "2023-10-17" @default.
- W3030551035 title "Effects of pregabalin on the postoperative analgesia in patients with lower abdominal surgery" @default.
- W3030551035 doi "https://doi.org/10.3760/cma.j.issn.1673-4378.2012.08.002" @default.
- W3030551035 hasPublicationYear "2012" @default.
- W3030551035 type Work @default.
- W3030551035 sameAs 3030551035 @default.
- W3030551035 citedByCount "0" @default.
- W3030551035 crossrefType "journal-article" @default.
- W3030551035 hasAuthorship W3030551035A5041373689 @default.
- W3030551035 hasAuthorship W3030551035A5060120199 @default.
- W3030551035 hasConcept C141071460 @default.
- W3030551035 hasConcept C14184104 @default.
- W3030551035 hasConcept C2776277131 @default.
- W3030551035 hasConcept C2776468701 @default.
- W3030551035 hasConcept C2778891214 @default.
- W3030551035 hasConcept C2780120127 @default.
- W3030551035 hasConcept C2780820201 @default.
- W3030551035 hasConcept C42219234 @default.
- W3030551035 hasConcept C71924100 @default.
- W3030551035 hasConceptScore W3030551035C141071460 @default.
- W3030551035 hasConceptScore W3030551035C14184104 @default.
- W3030551035 hasConceptScore W3030551035C2776277131 @default.
- W3030551035 hasConceptScore W3030551035C2776468701 @default.
- W3030551035 hasConceptScore W3030551035C2778891214 @default.
- W3030551035 hasConceptScore W3030551035C2780120127 @default.
- W3030551035 hasConceptScore W3030551035C2780820201 @default.
- W3030551035 hasConceptScore W3030551035C42219234 @default.
- W3030551035 hasConceptScore W3030551035C71924100 @default.
- W3030551035 hasIssue "08" @default.
- W3030551035 hasLocation W30305510351 @default.
- W3030551035 hasOpenAccess W3030551035 @default.
- W3030551035 hasPrimaryLocation W30305510351 @default.
- W3030551035 hasRelatedWork W2315563770 @default.
- W3030551035 hasRelatedWork W2327679486 @default.
- W3030551035 hasRelatedWork W2330803232 @default.
- W3030551035 hasRelatedWork W2347688156 @default.
- W3030551035 hasRelatedWork W2357893761 @default.
- W3030551035 hasRelatedWork W2361596778 @default.
- W3030551035 hasRelatedWork W2373637755 @default.
- W3030551035 hasRelatedWork W2383669490 @default.
- W3030551035 hasRelatedWork W2385542184 @default.
- W3030551035 hasRelatedWork W2386876793 @default.
- W3030551035 hasRelatedWork W2389343651 @default.
- W3030551035 hasRelatedWork W2853415192 @default.
- W3030551035 hasRelatedWork W2910524660 @default.
- W3030551035 hasRelatedWork W3029116369 @default.
- W3030551035 hasRelatedWork W3029705112 @default.
- W3030551035 hasRelatedWork W3030279378 @default.
- W3030551035 hasRelatedWork W3032500976 @default.
- W3030551035 hasRelatedWork W3192644458 @default.
- W3030551035 hasRelatedWork W3208665489 @default.
- W3030551035 hasRelatedWork W2912282424 @default.
- W3030551035 hasVolume "33" @default.
- W3030551035 isParatext "false" @default.
- W3030551035 isRetracted "false" @default.
- W3030551035 magId "3030551035" @default.
- W3030551035 workType "article" @default.