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- W3030605429 abstract "Objective To analyze the incidence,mortality and survival rates of pancreatic cancer in Pudong New Area of Shanghai from 2002 to 2010.Methods The residents in Pudong New Area of Shanghai were recruited in this study during the period 2002 ~ 2010,the incidence,mortality were calculated according to different age groups and genders.The standardized morbidity and mortality of pancreatic cancer were calculated by world standard population.Logarithmic linear regression was used to calculate the annual percentage change (APC) of incidence and mortality.The 1 ~ 5 year survival of pancreatic cancer patients was analyzed by Kaplan-Meier method and COX regression analysis,and the survival of patients with different TNM staging,with or without operation was determined.Results Among 3089 newly occurred pancreatic cancer cases during 2002 ~ 2010,1707 and 1382 cases were males and females,respectively,with an average age of (69 ± 12) and (73 ± 12) years old,the crude incidence for both genders was 13.32/100 000,and it was 14.71/100 000 for males,which was higher than that in females (11.93/100 000).The ratio of male and female for incidence of age standardize was 1.57:1.There were 2963 death in total,including 1627 males and 1336 females,with a crude mortality rate of 12.78/100 000.The crude mortality rate for males was 14.02/100 000,which was higher than that in females (11.53/100 000).The ratio of male and female ASR for mortality was 1.55:1.Both incidence and mortality significantly increased for males aged over 35 and females aged over 40.The peak of morbidity and mortality appeared in male over 80 years old,and in female over 85 years old.The 1 ~ 5 year survival rates of pancreatic cancer patients were 16.59%,7.31%,5.23%,4.33% and 3.87%,respectively.The differences in 1 ~5 year survival rates between surgical and non-surgical management groups were statistically significant (P < 0.05).The median survival time of TNM 0 ~ Ⅱ,Ⅲ and Ⅳ staging was (250.00 ± 33.37),(224.00 ± 15.82),(86.00 ± 4.52) d.There was a statistically significant difference among the survival of TNM-Ⅳ and TNM 0 ~ Ⅰ,TNM Ⅲ (P < 0.001).Conclusions The incidence and mortality of pancreatic cancer in males are higher than those in females in Pudong New Area of Shanghai.The survival is associated with TNM staging at diagnosis and whether surgical operation is performed.Key words: Pancreatic neoplasms ; Epidemiologic studies ; Data collection; Incidence ; Mortality; Survival rate" @default.
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- W3030605429 date "2013-10-20" @default.
- W3030605429 modified "2023-10-15" @default.
- W3030605429 title "Incidence, mortality and survival rates of pancreatic cancer among residents in Pudong New Area of Shanghai from 2002 to 2010" @default.
- W3030605429 doi "https://doi.org/10.3760/cma.j.issn.1674-1935.2013.05.003" @default.
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