FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3030638873> ?p ?o ?g. }

• W3030638873 endingPage "662" @default.
• W3030638873 startingPage "656" @default.
• W3030638873 abstract "ObjectiveTo investigate the clinical efficacy and safety of caffeine citrate combined with duo positive airway pressure (DuoPAP) in treatment of premature infants with respiratory distress syndrome (RDS).MethodsFrom January 2016 to November 2017, a total of 90 preterm infants with RDS (28 weeks ≤gestational age <32 weeks) who were hospitalized in the Affiliated Xuzhou Hospital of Southeast University, were chosen as research subjects. They were randomly divided into two groups by random number table method. In the combined treatment group (n=47), they were given caffeine citrate combined with DuoPAP; and in the control group (n=43), they were given DuoPAP without caffeine citrate. The general clinical data, results of blood gas analysis and indicators of respiratory function at 0 h, 24 h and 48 h of breath support therapy, clinical efficacy, related complications of breath support therapy and adverse drug reactions between two groups of premature infants were compared statistically by independent-samples t test, chi-square test and Kruskal-Wallis H rank sum test. The study was reviewed and approved by the Medical Ethics Committee of the Affiliated Xuzhou Hospital of Southeast University (Approval Number: 2015 No. 32), and the informed consents were signed by all the guardians of preterm infants.Results① There were no significant differences between two groups in general clinical data including the proportion of male, gravidity, gestational age, birth weight, 1 min and 5 min Apgar scores after birth of RDS premature infants; and the rate of premature rupture of membranes, cesarean section rate, glucocorticoid application rate within 24 h to 7 d before delivery, the incidence rate of hypertensive disorders complicating pregnancy of mother (P>0.05). ② There were no significant differences between two groups of RDS premature infants in pH value, partial pressure of arterial carbon dioxide (PaCO2), partial pressure of arterial oxygen (PaO2) and PaO2/fraction of inspired oxygen (P/F) at 0 h of breath support therapy, also pH value at 24 h, 48 h after breath support therapy (P>0.05). The PaO2 and P/F of RDS premature infants in combined treatment group at 24 h, 48 h after breath support therapy were higher than those in control group, while PaCO2 were lower than that in control group, and the differences were statistically significant (24 h: t=3.431, P=0.017; t=3.451, P=0.047; t=-4.241, P=0.008. 48 h: t=3.238, P=0.048; t=3.576, P=0.009; t=-3.527, P=0.031). ③ The duration of DuoPAP ventilation therapy and total oxygen inhaling, the days of hospitalization, the times of apnea, the failure rate of withdrew from the machine, the usage rate of one dose of pulmonary surfactant (PS) in combined treatment group were 3.0 d (1.0-14.0 d), 7.5 d (4.0-21.0 d), 16.0 d (6.0-28.0 d), 10.0 h(7.0-14.0), 8.5% and 21.3%, which were significant shorter, or less, or lower than those in control group, which were 5.5 d (2.0-18.0 d), 11.5 d (6.0-32.0 d), 21.0 d (7.0-35.0 d), 24.0 (18.0-28.0), 25.6% and 41.9%, and all the differences were statistically significant (Z=-2.030, P=0.012; Z=-2.129, P=0.011; Z=-2.889, P=0.009; Z=-2.105, P=0.018; χ2=4.712, P=0.030; χ2=4.439, P=0.035). ④ There were no significant differences between two groups of RDS premature infants in related complication of breath support therapy including air leak syndrome, bronchopulmonary dysplasia (BPD), retinopathy of prematurity (ROP), periventricular-intraventricular hemorrhage (PVH-IVH) and neonatal necrotic enterocolitis (NEC), also caffeine associated adverse reactions including incidence rate of feeding intolerance and heart rate abnormal (P>0.05).ConclusionsCaffeine citrate combined with DuoPAP treatment strategy to premature infants with RDS can effectively improve oxygenation, reduce CO2 retention, shorten the duration of noninvasive mechanical ventilation and total oxygen inhaling, increase the success rate of machine withdrawal. It is safe and effective.Key words: Continuous positive airway pressure; Caffeine citrate; Respiratory distress syndrome, newborn; Retinopathy of prematurity; Infant, premature" @default.
• W3030638873 created "2020-06-05" @default.
• W3030638873 creator A5006464250 @default.
• W3030638873 creator A5019303133 @default.
• W3030638873 creator A5020655239 @default.
• W3030638873 creator A5038945070 @default.
• W3030638873 creator A5041317124 @default.
• W3030638873 date "2018-12-01" @default.
• W3030638873 modified "2023-10-11" @default.
• W3030638873 title "Caffeine citrate combined with duo positive airway pressure in treatment of premature infants with respiratory distress syndrome" @default.
• W3030638873 doi "https://doi.org/10.3877/cma.j.issn.1673-5250.2018.06.006" @default.
• W3030638873 hasPublicationYear "2018" @default.
• W3030638873 type Work @default.
• W3030638873 sameAs 3030638873 @default.
• W3030638873 citedByCount "0" @default.
• W3030638873 crossrefType "journal-article" @default.
• W3030638873 hasAuthorship W3030638873A5006464250 @default.
• W3030638873 hasAuthorship W3030638873A5019303133 @default.
• W3030638873 hasAuthorship W3030638873A5020655239 @default.
• W3030638873 hasAuthorship W3030638873A5038945070 @default.
• W3030638873 hasAuthorship W3030638873A5041317124 @default.
• W3030638873 hasConcept C131872663 @default.
• W3030638873 hasConcept C141983124 @default.
• W3030638873 hasConcept C187212893 @default.
• W3030638873 hasConcept C2775867611 @default.
• W3030638873 hasConcept C2776006263 @default.
• W3030638873 hasConcept C2777102558 @default.
• W3030638873 hasConcept C2778052368 @default.
• W3030638873 hasConcept C2778376644 @default.
• W3030638873 hasConcept C2779234561 @default.
• W3030638873 hasConcept C2779547634 @default.
• W3030638873 hasConcept C2780395437 @default.
• W3030638873 hasConcept C42219234 @default.
• W3030638873 hasConcept C54355233 @default.
• W3030638873 hasConcept C66322754 @default.
• W3030638873 hasConcept C71924100 @default.
• W3030638873 hasConcept C86803240 @default.
• W3030638873 hasConceptScore W3030638873C131872663 @default.
• W3030638873 hasConceptScore W3030638873C141983124 @default.
• W3030638873 hasConceptScore W3030638873C187212893 @default.
• W3030638873 hasConceptScore W3030638873C2775867611 @default.
• W3030638873 hasConceptScore W3030638873C2776006263 @default.
• W3030638873 hasConceptScore W3030638873C2777102558 @default.
• W3030638873 hasConceptScore W3030638873C2778052368 @default.
• W3030638873 hasConceptScore W3030638873C2778376644 @default.
• W3030638873 hasConceptScore W3030638873C2779234561 @default.
• W3030638873 hasConceptScore W3030638873C2779547634 @default.
• W3030638873 hasConceptScore W3030638873C2780395437 @default.
• W3030638873 hasConceptScore W3030638873C42219234 @default.
• W3030638873 hasConceptScore W3030638873C54355233 @default.
• W3030638873 hasConceptScore W3030638873C66322754 @default.
• W3030638873 hasConceptScore W3030638873C71924100 @default.
• W3030638873 hasConceptScore W3030638873C86803240 @default.
• W3030638873 hasIssue "6" @default.
• W3030638873 hasLocation W30306388731 @default.
• W3030638873 hasOpenAccess W3030638873 @default.
• W3030638873 hasPrimaryLocation W30306388731 @default.
• W3030638873 hasRelatedWork W1975431098 @default.
• W3030638873 hasRelatedWork W1987546432 @default.
• W3030638873 hasRelatedWork W2065466817 @default.
• W3030638873 hasRelatedWork W2153001272 @default.
• W3030638873 hasRelatedWork W2321433249 @default.
• W3030638873 hasRelatedWork W2360082306 @default.
• W3030638873 hasRelatedWork W2364003635 @default.
• W3030638873 hasRelatedWork W2384224621 @default.
• W3030638873 hasRelatedWork W2417859025 @default.
• W3030638873 hasRelatedWork W2767278523 @default.
• W3030638873 hasRelatedWork W2769189687 @default.
• W3030638873 hasRelatedWork W2777377676 @default.
• W3030638873 hasRelatedWork W3026226901 @default.
• W3030638873 hasRelatedWork W3029083303 @default.
• W3030638873 hasRelatedWork W3029511728 @default.
• W3030638873 hasRelatedWork W3030210929 @default.
• W3030638873 hasRelatedWork W3030386757 @default.
• W3030638873 hasRelatedWork W3031247147 @default.
• W3030638873 hasRelatedWork W3031346611 @default.
• W3030638873 hasRelatedWork W3170838535 @default.
• W3030638873 hasVolume "14" @default.
• W3030638873 isParatext "false" @default.
• W3030638873 isRetracted "false" @default.
• W3030638873 magId "3030638873" @default.
• W3030638873 workType "article" @default.