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- W3030650884 abstract "ObjectiveTo explore the CT findings of benign and malignant pancreatic neuroendocrine tumors and improve its diagnostic accuracy.MethodsThe clinical information and enhanced CT findings of 96 cases with pathologically-proved pancreatic neuroendocrine tumors were retrospectively reviewed. The CT findings were evaluated by several factors, which included tumor size, morphology, location, internal composition, calcification, separation, bile duct and pancreatic duct dilation and CT value.ResultsAll cases were divided into benign or malignant according to pathological grades, and benign group involved 40 cases with 41 lesions, while malignant group involved 56 cases with 59 lesions. The size of malignant lesions was significantly larger than that of benign lesions (median size 6.0 cm vs 2.2 cm), the shape of the lesions was irregular, and was mainly cystic solid, and mottling, curve shape, clumps calcification was present, then the bile duct and pancreatic duct was mild to moderately dilated, and the difference between the two groups was statistically significant (P<0.05). But the difference of tumor location, separation was not significant. 45.76%(27/59) of the malignant lesions reached the peak value in arterial phase, and 44.07%(26/59) reached the peak value in venous phase; while 68.29%(28/41) of the benign lesions reached the peak value in arterial phase, and 31.71%(13/41) reached the peak value in venous phase. The CT values of malignant lesions in plain CT scanning, arterial phase, venous phase, balance phase were (39.02±7.53), (121.20±54.73), (125.25±40.77), (101.41±28.68) Hu, while they were (41.49±8.59), (144.73±53.95), (157.05±44.72), (121.02±29.80) Hu in benign group. In plain CT scanning, the difference of CT value between malignant and benign lesions was not significant; but in the enhanced phase, the CT value of malignant lesions was significantly lower than that of benign lesions, and the difference was statistically significant (P<0.05).ConclusionsThe lesion with its size ≥ 3.0 cm, irregular morphology, cystic necrosis, calcification, pancreatic and bile duct dilatation is suggestive of malignancy tumor. The average CT values of malignant group are lower than those of the benign group in arterial, venous and balance phases.Key words: Pancreas; Neuroendocrine tumor; Tomography, X-ray computed; Diagnosis" @default.
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- W3030650884 date "2015-08-20" @default.
- W3030650884 modified "2023-09-24" @default.
- W3030650884 title "Analysis of CT findings of benign and malignant pancreatic neuroendocrine tumors" @default.
- W3030650884 doi "https://doi.org/10.3760/cma.j.issn.1674-1935.2015.04.006" @default.
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