Matches in SemOpenAlex for { <https://semopenalex.org/work/W3030674966> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W3030674966 endingPage "326" @default.
- W3030674966 startingPage "322" @default.
- W3030674966 abstract "ObjectiveTo investigate the expression and significance of cellular inhibitor of protein phosphatase 2A (CIP2A), bcl-2 and p63 in papillary thyroid cancer (PTC).MethodsUsing immunohistochemistry to detect the expression of CIP2A, bcl-2 and p63 in 30 cases of nodular goiter (NG), 30 cases of thyroid adenoma (TA) and 57 cases of PTC [including classical PTC (cPTC) 20 cases, papillary microcarcinoma (PMC) 20 cases, follicular thyroid papillary carcinoma (FPTC) 7 cases].ResultsIn NG group, TA group and PTC group, positive rates of CIP2A were 0, 0 and 94.74% (54/57), respectively. The differences were statistically significant. In NG group, TA group and PTC group, positive rates of bcl-2 were 16.67% (5/30), 13.33% (4/30) and 85.96% (49/57), respectively. The differences were statistically significant. In each group, positive rates of p63 were 6.67% (2/30), 3.33% (1/30) and 5.26% (3/57), respectively, no significant difference among them. In PTC, expression of CIP2A and bcl-2 were significantly higher than in NG and TA (χ2= 105.56, P= 0.00; χ2= 58.95, P= 0.00). Furthermore, the expression of CIP2A and bcl-2 had correlation in PTC (r= 0.94, P= 0.00). The expression of CIP2A, bcl-2 and p63 had no significantly difference among all the PTC subtype(χ2 values were 2.02, 2.64, 1.85; all P > 0.05). The expression of CIP2A, bcl-2 and p63 was not associated with patients'age, sex, site, lymph node metastasis (all P > 0.05).ConclusionsHigh expression of CIP2A and bcl-2 is associated with PTC, and the expression of CIP2A and bcl-2 has correlation in PTC. The expression of p63 has no correlation with PTC.Key words: Thyroid neoplasms; Papilloma; Cellular inhibitor of protein phosphatase 2A; bcl-2; p63" @default.
- W3030674966 created "2020-06-05" @default.
- W3030674966 creator A5004014741 @default.
- W3030674966 creator A5012848570 @default.
- W3030674966 creator A5043980945 @default.
- W3030674966 creator A5062290295 @default.
- W3030674966 creator A5086662417 @default.
- W3030674966 date "2017-05-28" @default.
- W3030674966 modified "2023-10-17" @default.
- W3030674966 title "Expression of CIP2A, bcl-2 and p63 in papillary thyroid cancer and their significances" @default.
- W3030674966 doi "https://doi.org/10.3760/cma.j.issn.1006-9801.2017.05.008" @default.
- W3030674966 hasPublicationYear "2017" @default.
- W3030674966 type Work @default.
- W3030674966 sameAs 3030674966 @default.
- W3030674966 citedByCount "0" @default.
- W3030674966 crossrefType "journal-article" @default.
- W3030674966 hasAuthorship W3030674966A5004014741 @default.
- W3030674966 hasAuthorship W3030674966A5012848570 @default.
- W3030674966 hasAuthorship W3030674966A5043980945 @default.
- W3030674966 hasAuthorship W3030674966A5062290295 @default.
- W3030674966 hasAuthorship W3030674966A5086662417 @default.
- W3030674966 hasConcept C126322002 @default.
- W3030674966 hasConcept C134018914 @default.
- W3030674966 hasConcept C142724271 @default.
- W3030674966 hasConcept C187785154 @default.
- W3030674966 hasConcept C204232928 @default.
- W3030674966 hasConcept C2776254400 @default.
- W3030674966 hasConcept C2779761222 @default.
- W3030674966 hasConcept C2993294228 @default.
- W3030674966 hasConcept C526584372 @default.
- W3030674966 hasConcept C71924100 @default.
- W3030674966 hasConcept C90924648 @default.
- W3030674966 hasConceptScore W3030674966C126322002 @default.
- W3030674966 hasConceptScore W3030674966C134018914 @default.
- W3030674966 hasConceptScore W3030674966C142724271 @default.
- W3030674966 hasConceptScore W3030674966C187785154 @default.
- W3030674966 hasConceptScore W3030674966C204232928 @default.
- W3030674966 hasConceptScore W3030674966C2776254400 @default.
- W3030674966 hasConceptScore W3030674966C2779761222 @default.
- W3030674966 hasConceptScore W3030674966C2993294228 @default.
- W3030674966 hasConceptScore W3030674966C526584372 @default.
- W3030674966 hasConceptScore W3030674966C71924100 @default.
- W3030674966 hasConceptScore W3030674966C90924648 @default.
- W3030674966 hasIssue "05" @default.
- W3030674966 hasLocation W30306749661 @default.
- W3030674966 hasOpenAccess W3030674966 @default.
- W3030674966 hasPrimaryLocation W30306749661 @default.
- W3030674966 hasRelatedWork W2046508477 @default.
- W3030674966 hasRelatedWork W2120582434 @default.
- W3030674966 hasRelatedWork W2144440698 @default.
- W3030674966 hasRelatedWork W2352095559 @default.
- W3030674966 hasRelatedWork W2363412077 @default.
- W3030674966 hasRelatedWork W2364036608 @default.
- W3030674966 hasRelatedWork W2367769889 @default.
- W3030674966 hasRelatedWork W2371282729 @default.
- W3030674966 hasRelatedWork W2373862746 @default.
- W3030674966 hasRelatedWork W2375101375 @default.
- W3030674966 hasRelatedWork W2379914667 @default.
- W3030674966 hasRelatedWork W2380853675 @default.
- W3030674966 hasRelatedWork W2383452856 @default.
- W3030674966 hasRelatedWork W2383743058 @default.
- W3030674966 hasRelatedWork W2385403339 @default.
- W3030674966 hasRelatedWork W2387179346 @default.
- W3030674966 hasRelatedWork W2390287734 @default.
- W3030674966 hasRelatedWork W2390585082 @default.
- W3030674966 hasRelatedWork W2913663580 @default.
- W3030674966 hasRelatedWork W70922831 @default.
- W3030674966 hasVolume "29" @default.
- W3030674966 isParatext "false" @default.
- W3030674966 isRetracted "false" @default.
- W3030674966 magId "3030674966" @default.
- W3030674966 workType "article" @default.