Matches in SemOpenAlex for { <https://semopenalex.org/work/W3030682023> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W3030682023 endingPage "58" @default.
- W3030682023 startingPage "55" @default.
- W3030682023 abstract "ObjectiveTo investigate the in vivo radioprotective effect of adenosine triphosphate(ATP) on radiation damage induced by high dose γ-ray ionizing radiation(IR) in mice.MethodsSpecific pathogen-free C57BL/6 female mice were randomly divided into IR group and IR+ATP group by body weight, with 10 mice in each group. All the mice were treated with a 8 Gy one-time and high-dose whole body γ-ray irradiation. Within 6 h after irradiation, mice were injected intramuscular injection of 150 μl sodium chloride solution (9 g/L) for IR group, and 150 μl ATP solution (6 mg/kg) for IR+ATP group, respectively. The drug was administered once a day until the death of the animal. The mean survival days, survival rate, body weight and major organ coefficients in both groups were measured.ResultsThe average survival days of mice in IR group and IR+ATP group were 6.5 d and 9.6 d, respectively. The survival rate of the mice in IR+ATP group was higher than that in IR group (P<0.01). The body weight values of the mice in IR+ATP group was higher than that in IR group on the after the 4th day post-irradiation, and the differences were statistically significant (all P<0.05). Except for heart and stomach, the organ coefficients of liver, spleen, lung, and kidney in IR+ATP mice were higher than those in IR group, and the differences were statistically significant (all P<0.05).ConclusionATP has certain radiation protection effect, and it can reduce the radiation damage of mice induced by high-dose (8 Gy) γ-ray IR so as to increase the survival rate.Key words: Adenosine triphosphate; Ionizing radiation; Radioprotective effect" @default.
- W3030682023 created "2020-06-05" @default.
- W3030682023 creator A5018186999 @default.
- W3030682023 creator A5034551676 @default.
- W3030682023 creator A5045027028 @default.
- W3030682023 creator A5045455057 @default.
- W3030682023 creator A5089555055 @default.
- W3030682023 date "2018-02-28" @default.
- W3030682023 modified "2023-09-28" @default.
- W3030682023 title "Radioprotective effect of ATP on mice irradiated with a lethal dose of γ-ray" @default.
- W3030682023 doi "https://doi.org/10.3760/cma.j.issn.1673-4181.2018.01.009" @default.
- W3030682023 hasPublicationYear "2018" @default.
- W3030682023 type Work @default.
- W3030682023 sameAs 3030682023 @default.
- W3030682023 citedByCount "0" @default.
- W3030682023 crossrefType "journal-article" @default.
- W3030682023 hasAuthorship W3030682023A5018186999 @default.
- W3030682023 hasAuthorship W3030682023A5034551676 @default.
- W3030682023 hasAuthorship W3030682023A5045027028 @default.
- W3030682023 hasAuthorship W3030682023A5045455057 @default.
- W3030682023 hasAuthorship W3030682023A5089555055 @default.
- W3030682023 hasConcept C111337013 @default.
- W3030682023 hasConcept C121332964 @default.
- W3030682023 hasConcept C126322002 @default.
- W3030682023 hasConcept C134018914 @default.
- W3030682023 hasConcept C147583825 @default.
- W3030682023 hasConcept C150903083 @default.
- W3030682023 hasConcept C178790620 @default.
- W3030682023 hasConcept C18231593 @default.
- W3030682023 hasConcept C185544564 @default.
- W3030682023 hasConcept C185592680 @default.
- W3030682023 hasConcept C207001950 @default.
- W3030682023 hasConcept C2777544843 @default.
- W3030682023 hasConcept C2780091579 @default.
- W3030682023 hasConcept C2780931953 @default.
- W3030682023 hasConcept C71924100 @default.
- W3030682023 hasConcept C86803240 @default.
- W3030682023 hasConcept C98274493 @default.
- W3030682023 hasConceptScore W3030682023C111337013 @default.
- W3030682023 hasConceptScore W3030682023C121332964 @default.
- W3030682023 hasConceptScore W3030682023C126322002 @default.
- W3030682023 hasConceptScore W3030682023C134018914 @default.
- W3030682023 hasConceptScore W3030682023C147583825 @default.
- W3030682023 hasConceptScore W3030682023C150903083 @default.
- W3030682023 hasConceptScore W3030682023C178790620 @default.
- W3030682023 hasConceptScore W3030682023C18231593 @default.
- W3030682023 hasConceptScore W3030682023C185544564 @default.
- W3030682023 hasConceptScore W3030682023C185592680 @default.
- W3030682023 hasConceptScore W3030682023C207001950 @default.
- W3030682023 hasConceptScore W3030682023C2777544843 @default.
- W3030682023 hasConceptScore W3030682023C2780091579 @default.
- W3030682023 hasConceptScore W3030682023C2780931953 @default.
- W3030682023 hasConceptScore W3030682023C71924100 @default.
- W3030682023 hasConceptScore W3030682023C86803240 @default.
- W3030682023 hasConceptScore W3030682023C98274493 @default.
- W3030682023 hasIssue "1" @default.
- W3030682023 hasLocation W30306820231 @default.
- W3030682023 hasOpenAccess W3030682023 @default.
- W3030682023 hasPrimaryLocation W30306820231 @default.
- W3030682023 hasRelatedWork W2022692929 @default.
- W3030682023 hasRelatedWork W2100863459 @default.
- W3030682023 hasRelatedWork W2112025620 @default.
- W3030682023 hasRelatedWork W2128635760 @default.
- W3030682023 hasRelatedWork W2358703943 @default.
- W3030682023 hasRelatedWork W2365758854 @default.
- W3030682023 hasRelatedWork W2377190991 @default.
- W3030682023 hasRelatedWork W2391787248 @default.
- W3030682023 hasRelatedWork W2398802827 @default.
- W3030682023 hasRelatedWork W2409148036 @default.
- W3030682023 hasRelatedWork W2417112802 @default.
- W3030682023 hasRelatedWork W2488474761 @default.
- W3030682023 hasRelatedWork W2620008720 @default.
- W3030682023 hasRelatedWork W2770378433 @default.
- W3030682023 hasRelatedWork W2886151905 @default.
- W3030682023 hasRelatedWork W3028758996 @default.
- W3030682023 hasRelatedWork W3030045646 @default.
- W3030682023 hasRelatedWork W3030143471 @default.
- W3030682023 hasRelatedWork W3031476356 @default.
- W3030682023 hasRelatedWork W3032859503 @default.
- W3030682023 hasVolume "41" @default.
- W3030682023 isParatext "false" @default.
- W3030682023 isRetracted "false" @default.
- W3030682023 magId "3030682023" @default.
- W3030682023 workType "article" @default.