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• W3030702010 abstract "Purpose: To evaluate the association of scleral contact lens (SCL) use on the risk for keratoplasty for people with keratoconus. Methods: The electronic health records of patients receiving eye care at the University of Michigan Kellogg Eye Center between August 1, 2012, and December 31, 2018, were reviewed. Patients with a diagnostic code of keratoconus or corneal ectasia, no previous history of keratoplasty, and for whom data were available for both eyes were included. Using a multivariable Cox regression model, associations between SCL use and keratoplasty were tested and adjusted for sociodemographic factors, maximum keratometry, and current contact lens (CL) use. Results: Two thousand eight hundred six eyes met the inclusion criteria. CL use in each eye was 36.2% with no CL, 7.2% soft, 33.9% rigid gas permeable (RGP), and 22.7% scleral. A total of 3.2% of eyes underwent keratoplasty. In the adjusted model, SCL or RGP CL use significantly lowered the hazard of undergoing keratoplasty (HR = 0.19, 95% confidence interval [CI] 0.09–0.39, P < 0.0001 and HR = 0.30, 95% CI 0.17–0.52, P < 0.0001, respectively) when compared with no CL use. Factors associated with increased risk of keratoplasty were black race as compared to white (HR = 1.87, 95% CI 1.10–3.16, P = 0.02), younger age (HR = 0.92 per 5-year increment, 95% CI 0.86–0.99, P = 0.032), and lower socioeconomic status (HR = 1.08 per 5-point increase in the Area Deprivation Index, 95% CI 1.03–1.13, P = 0.0008). Keratoplasty was not associated with sex, insurance, or maximum keratometry. Conclusions: Physicians should maximize the use of scleral or RGP CL because patients who successfully use CL have almost one-fifth the risk of undergoing keratoplasty." @default.
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• W3030702010 date "2020-06-07" @default.
• W3030702010 modified "2023-09-24" @default.
• W3030702010 title "Impact of Scleral Contact Lens Use on the Rate of Corneal Transplantation for Keratoconus" @default.
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• W3030702010 doi "https://doi.org/10.1097/ico.0000000000002388" @default.
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