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- W3030710360 abstract "ObjectiveTo evaluate the clinical effect for transcatheter closure of intracristal ventricular septal defects (IVSD) using duct occluder.MethodsBetween Jun.2012 and Sep.2013, implantation of duct occluder was conducted in 27 IVSD patients, which was compared with acentric ventricular septal occluder attempted in 53 IVSD patients.The transthoracic echocardiography, electrocardiography, and clinical examination were observed at 24 hours, and after 1, 3, 6 and 12 months follows-up.ResultsImplantation of duct occluders were achieved in 26(96.23%) patients and implantation of acentric ventricular septal occluder in 42(79.25%) patients.The mean follow-up time was 6.78 months (1-17 months). The procedure time, fluoroscopic time and residual shunt were not statistically different between the 2 groups(all P>0.05). The size of VSD(t=-3.124, P=0.003) and occluder diameter (t=-4.285, P<0.001)were smaller and the procedure success rate was higher in the duct occluder group (χ2=9.099, P=0.011). Left ventricular end diastolic dimension, left atrial diameter, left ventricular end diastolic dimension, right ventricular end diastolic dimension and pulmonary artery diameter were decreased significantly (F=57.62, 5.002, 4.754, 2.782, P=0.000, 0.033, 0.001, 0.030)after surgical procedure compared with those before procedure, except for the right atrial diameter and left ventricular ejection fraction.No new serious aortic regurgitation or increased mitral regurgitation, tricuspid regurgitation was shown after procedure in 2 groups.Complete left bundle branch block occurred in 2 patients respectively, pericardial effusion and thromboembolism of right femoral artery occurred in 1 patient in the acentric ventricular septal occluder group.ConclusionsThe duct occluder for IVSD closure has presented a good result, without serious complications, which provides a new method for IVSD closure.Further studies are necessary to determine the long-term results in a larger population of patients.Key words: Congenital heart disease; Ventricular septal defect; Interventional therapy" @default.
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- W3030710360 date "2014-05-20" @default.
- W3030710360 modified "2023-09-26" @default.
- W3030710360 title "Evaluation for the clinical effect of duct occluder in treatment of intracristal ventricular septal defect" @default.
- W3030710360 doi "https://doi.org/10.3760/cma.j.issn.2095-428x.2014.10.011" @default.
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