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- W3030718770 abstract "Micronuclei (MN) is also called satellite micronuclei.It is an abnormal structure in eukaryotic cells and a manifestation of genomic instability.MN can be divided into chromosome-type micronuclei and double minute-type micronuclei based on the contents of it.These two types of micronuclei exist and arise independently in a cell.A double minute (DM)is an extrachromosomal element that is commonly seen in tumor cells.Therefore,studying the biology of DM-type micronuclei will enable us to understand how these extrachromosomal structures may be retained within a cell or expelled from the cell.Here we summarize the molecular mechanism and the biology of DM-type micronuclei.Key words: Micronuclei; DM-type micronuclei; Tumor; Molecular mechanism" @default.
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- W3030718770 date "2013-08-15" @default.
- W3030718770 modified "2023-09-27" @default.
- W3030718770 title "Molecular mechanism of the origin of micronuclei from double minutes" @default.
- W3030718770 doi "https://doi.org/10.3760/cma.j.issn.1673-4386.2013.04.003" @default.
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