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- W3030757067 abstract "目的比较度洛西汀与帕罗西汀治疗以躯体疼痛为主诉的老年抑郁症患者的疗效和安全性。方法将90例以躯体疼痛为主诉的老年抑郁症患者随机分成两组。分别口服度洛西汀和帕洛西汀治疗，疗程为6周。根据汉密尔顿抑郁量表（HAMD）减分率评定抗抑郁疗效。根据疼痛量表（MOSPM）评定躯体疼痛改善效果。用副反应量表（TESS）评定用药的安全性。结果度洛西汀组有效率88.9%（40/45），帕罗西汀组有效率82.2%（37/45）。在治疗1、2、4周末，两组HAMD差异均有统计学意义（P 0.05）。在治疗1、2、4、6周后度洛西汀组MOSPM评分明显低于帕罗西汀组，差异具有统计学意义（均P<0.05）。结论度洛西汀治疗老年抑郁症总体疗效与帕罗西汀相当，但度洛西汀起效快，且能较快改善躯体疼痛症状，安全性高，依从性好，比帕罗西汀更适合老年抑郁症伴躯体疼痛患者的治疗。" @default.
- W3030757067 created "2020-06-05" @default.
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- W3030757067 date "2017-09-01" @default.
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- W3030757067 title "Duloxetine versus paroxtine for elderly patients with depression whose main symptom was body pain" @default.
- W3030757067 doi "https://doi.org/10.3760/cma.j.issn.1007-1245.2017.17.030" @default.
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