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- W3030758467 abstract "Objective:To explore the diagnostic value of imaging for nodular bronchial carcinoid with ectopic adrenocorticotropic hormone syndrome (EAS) .Methods:The image data of two cases of patients with small nodular lung carcinoid with EAS in our hospital were retrospectively analyzed, including MRI and PET-CT, chest CT, bilateral inferior petrosal sinus sampling (BIPSS) and pulmonary nodule biopsy. Combined with the patients' clinical manifestation and laboratory examination, the imaging features of these cases were summarized through literature analysis to improve the diagnostic level.Results:Both patients had obvious symptoms of Cushing's syndrome (CS) , the adrenocorticotropic hormone (ACTH) of peripheral blood was significantly increased, and cortisol secretion had no circadian rhythm. MRI indicated that pituitary adenomas cannot be ruled out, BIPSS ruled out sources of pituitary ACTH adenoma. Because of the circular nodules found on chest CT, one case of ACTH tumor originated from lung carcinoid was confirmed by puncture biopsy of right upper pulmonary nodules, and the other case of left lower pulmonary nodules was treated by direct thoracoscopic surgery. Two patients had surgical resection of pathology, one was diagnosed with typical low differentiation bronchial carcinoid, the other case was atypical.Conclusions:Bronchial carcinoid is one of the most common causes of EAS. When lung nodules were found in CS patients, and MRI or BIPSS ruled out the source of pituitary ACTH adenoma, ectopic ACTH secretion should be alert to exclude pulmonary bronchial carcinoid. Biopsy or imaging follow-up is necessary, and early detection and surgical removal of the lung tumor are used to gain good curative effect.Key words: Cushing's syndrome; Ectopic adrenocorticotropic hormone syndrome; Bronchial carcinoid" @default.
- W3030758467 created "2020-06-05" @default.
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- W3030758467 date "2019-02-01" @default.
- W3030758467 modified "2023-09-26" @default.
- W3030758467 title "Imaging characteristics analysis on ectopic adrenocorticotropic hormone syndrome caused by nodular bronchial carcinoid" @default.
- W3030758467 doi "https://doi.org/10.3877/cma.j.issn.2095-5782.2019.01.014" @default.
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