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- W3030764584 abstract "Objective To explore the clinical features,treatments and prognosis of granulocytic sarcoma (GS).Methods Form 1st October 2005 to 31st July 2012,25 patients who were diagnosed as GS in the First Affiliated Hospital of Soochow University were included in this study.All of them were divided into transplantation group (n=6) and non transplantation group (n=19),according to whether accepted the treatment of chemotherapy combined with allogeneic hematopoietic stem cell transplantation (alloHSCT).A retrospective analysis was made of 25 cases GS patients including the clinical characteristics,pathologic presentation,treatment and outcome.The statistic difference was tested by using Kaplan-Meier survival analysis and line of Log Rank test.Results The predilection sites included breast,skin,lymph nodes,etc.The 3 years overall survival (OS) rate of transplantation group and non-transplantation group were 66.7％±27.2％ and 15.9％±9.5％,respectively.There was a significant difference of three-year OS rate between ransplantation group and non-transplantation group (x2=7.188,P＜0.05).Conclusions GS is a rarely diagnosed entity,and the prognosis is generally poor.The diagnosis of GS depends on immunopathology.The therapy with high dose of cytarabine containing is a proper treatment for GS.AlloHSCT may be a positive treatment of GS,but the benefit of the treatment and the long-term prognosis still needs to be further clinical observation.Key words: granulocytic sarcoma; acute myeloid leukemia; allogeneic hematopoietic stem cell transplant" @default.
- W3030764584 created "2020-06-05" @default.
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- W3030764584 date "2013-01-20" @default.
- W3030764584 modified "2023-09-23" @default.
- W3030764584 title "A Clinical Analysis of 25 Cases Granulocytic Sarcoma" @default.
- W3030764584 doi "https://doi.org/10.3760/cma.j.issn.1673-419x.2013.01.002" @default.
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