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- W3030768329 abstract "26 dog-models of hypersplenism were made by ligating the splenic veins. 40% urea was injected in to spleen via splenic artery. It is confirmed effective in treating hypersplenism and preserving the immune function as compared with the control group in hematological, immunological and patho-histological studies.9 patients ( 7 cases of hyperslenism, 1 of hereditary spherocytosis, and 1 of idiopathic thrombocytopenic purpura) were treated with 40% urea. Their ages ranged from 1.5 to 11 years, 6 males and 3 females. Ligation and intubation of the arterywere done through a la-parotomy. 40% urea 5 to 8 ml was injected into the splenic artery through the silicon tube every other day. The tube should be removed after 10 to 20 injections. 8 patients were fol-lowed-up in 6 to 30 months. The symptoms of hypersplenism disappeared, hematological and immunological findings were satisfactory, no signs of recurrence were proved. A long-term follow-up these patients should be made in the future." @default.
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- W3030768329 date "1987-03-15" @default.
- W3030768329 modified "2023-09-25" @default.
- W3030768329 title "Urea in Hypersplenism: An Experimental Study and Clincal Use" @default.
- W3030768329 doi "https://doi.org/10.3760/cma.j.issn.0253-3006.1987.02.003" @default.
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