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- W3030804536 abstract "Objective To explore the clinical efficacy and safety of isotretinoin erythromycin gel in the treatment of mild to moderate acne vulgaris. Methods A randomized,open,parallel,controlled clinical study was conducted.A total of 200 patients were enrolled in this study,in which 3 patients were excluded and 24 patients droped off during the study.Efficacy analysis was carried out in 197 patients and safety analysis in 173 patients.The patients were classified into trial group (n=87)and control group (n=86) to be treated with isotretinoin erythromycin gel or tretinoin cream once a night for 8 weeks,respectively.The clinical effects and adverse drug reactions were observed.Results The effective rates were 64.37 ％ (56/87) in trial group and 58.14 ％ (50/86) in control group with no statistical significance (P＞0.05).The rate of adverse reactions were 15.31％ in trial group and 14.14 ％ in control group with no statistical significance (P＞0.05).Conclusions Isotretinoin erythromycin gel is safe and effective in the treatment of mild to moderate acne vulgaris.Key words: Ache vulgaris; Isotretinoin; Erythromycin" @default.
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- W3030804536 date "2012-02-15" @default.
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- W3030804536 title "Clinical effects of Isotretinoin erythromycin gel in treatment of mild to moderate acne vulgaris" @default.
- W3030804536 doi "https://doi.org/10.3760/cma.j.issn.1671-0290.2012.01.012" @default.
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