Matches in SemOpenAlex for { <https://semopenalex.org/work/W3030836342> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W3030836342 endingPage "256" @default.
- W3030836342 startingPage "244" @default.
- W3030836342 abstract "Articular cartilage defect is a common joint damage, however, due to the particularity of cartilage tissue, its repair ability is limited. Thus, articular cartilage damage often changes to more severe osteoarthritis which brings huge pain and economic burden to patients. The development of cartilage tissue engineering brings good news to these patients, but also faces great challenges. Because of the characteristics of mesenchymal stem cells(MSCs) including autologous source, amplification and cartilage differentiation potential, MSCs are often used as the seed cells of cartilage tissue engineering and got widely attention. In the commonly used treatment strategy of articular cartilage differentiated from mesenchymal cells, in vitro pre culture and differentiation showed good therapeutic effects.The mesenchymal stem cells collected from the patient were concentrated, cultured and induced differentiation in vitro, a certain number of differentiated chondrocytes were obtained, and then the cells and culture matrix were transplanted to the patient together. However, the tissue engineering cartilage obtained from mesenchymal stem cells cannot fully meet the requirements of clinical treatment. Moreover, due to the differences of disease type, degree and individuality, there are various optimized factors for the treatment of MSCs derived tissue-engineered cartilage transplantation. For the same type of disease treatment, the optimization system still has no unified recognized standard. In order to obtain better adapt to the human body and meet the clinical requirements of articular cartilage, this review focus onoptimized factors of MSCs in the treatment of orthopedic diseases, summarize and analysis the research status, and discuss the induced factorsfrom three aspects: environmental factors, scaffold selection and seed cells.It provides an idea for using mesenchymal stem cells to obtain better tissue-engineered cartilage and to establish a better optimization system." @default.
- W3030836342 created "2020-06-05" @default.
- W3030836342 creator A5014505193 @default.
- W3030836342 creator A5024814320 @default.
- W3030836342 creator A5090953363 @default.
- W3030836342 date "2020-02-16" @default.
- W3030836342 modified "2023-09-24" @default.
- W3030836342 title "Optimization system of mesenchymal stem cells for tissue engineering chondrogenic differentiation" @default.
- W3030836342 doi "https://doi.org/10.3760/cma.j.issn.0253-2352.2020.04.007" @default.
- W3030836342 hasPublicationYear "2020" @default.
- W3030836342 type Work @default.
- W3030836342 sameAs 3030836342 @default.
- W3030836342 citedByCount "0" @default.
- W3030836342 crossrefType "journal-article" @default.
- W3030836342 hasAuthorship W3030836342A5014505193 @default.
- W3030836342 hasAuthorship W3030836342A5024814320 @default.
- W3030836342 hasAuthorship W3030836342A5090953363 @default.
- W3030836342 hasConcept C104317684 @default.
- W3030836342 hasConcept C105702510 @default.
- W3030836342 hasConcept C136229726 @default.
- W3030836342 hasConcept C13685319 @default.
- W3030836342 hasConcept C141071460 @default.
- W3030836342 hasConcept C142724271 @default.
- W3030836342 hasConcept C148738053 @default.
- W3030836342 hasConcept C171056886 @default.
- W3030836342 hasConcept C198826908 @default.
- W3030836342 hasConcept C204787440 @default.
- W3030836342 hasConcept C20875687 @default.
- W3030836342 hasConcept C2776164576 @default.
- W3030836342 hasConcept C2780550940 @default.
- W3030836342 hasConcept C28328180 @default.
- W3030836342 hasConcept C2911091166 @default.
- W3030836342 hasConcept C35496256 @default.
- W3030836342 hasConcept C49892992 @default.
- W3030836342 hasConcept C55493867 @default.
- W3030836342 hasConcept C71924100 @default.
- W3030836342 hasConcept C86803240 @default.
- W3030836342 hasConcept C95444343 @default.
- W3030836342 hasConceptScore W3030836342C104317684 @default.
- W3030836342 hasConceptScore W3030836342C105702510 @default.
- W3030836342 hasConceptScore W3030836342C136229726 @default.
- W3030836342 hasConceptScore W3030836342C13685319 @default.
- W3030836342 hasConceptScore W3030836342C141071460 @default.
- W3030836342 hasConceptScore W3030836342C142724271 @default.
- W3030836342 hasConceptScore W3030836342C148738053 @default.
- W3030836342 hasConceptScore W3030836342C171056886 @default.
- W3030836342 hasConceptScore W3030836342C198826908 @default.
- W3030836342 hasConceptScore W3030836342C204787440 @default.
- W3030836342 hasConceptScore W3030836342C20875687 @default.
- W3030836342 hasConceptScore W3030836342C2776164576 @default.
- W3030836342 hasConceptScore W3030836342C2780550940 @default.
- W3030836342 hasConceptScore W3030836342C28328180 @default.
- W3030836342 hasConceptScore W3030836342C2911091166 @default.
- W3030836342 hasConceptScore W3030836342C35496256 @default.
- W3030836342 hasConceptScore W3030836342C49892992 @default.
- W3030836342 hasConceptScore W3030836342C55493867 @default.
- W3030836342 hasConceptScore W3030836342C71924100 @default.
- W3030836342 hasConceptScore W3030836342C86803240 @default.
- W3030836342 hasConceptScore W3030836342C95444343 @default.
- W3030836342 hasIssue "04" @default.
- W3030836342 hasLocation W30308363421 @default.
- W3030836342 hasOpenAccess W3030836342 @default.
- W3030836342 hasPrimaryLocation W30308363421 @default.
- W3030836342 hasRelatedWork W1972067639 @default.
- W3030836342 hasRelatedWork W1978963556 @default.
- W3030836342 hasRelatedWork W1990992995 @default.
- W3030836342 hasRelatedWork W2006059997 @default.
- W3030836342 hasRelatedWork W2053119621 @default.
- W3030836342 hasRelatedWork W2078060475 @default.
- W3030836342 hasRelatedWork W2095894799 @default.
- W3030836342 hasRelatedWork W2270413144 @default.
- W3030836342 hasRelatedWork W2386754647 @default.
- W3030836342 hasRelatedWork W2465942780 @default.
- W3030836342 hasRelatedWork W2509813791 @default.
- W3030836342 hasRelatedWork W2575108039 @default.
- W3030836342 hasRelatedWork W2583167815 @default.
- W3030836342 hasRelatedWork W2583961593 @default.
- W3030836342 hasRelatedWork W2586232176 @default.
- W3030836342 hasRelatedWork W2590369772 @default.
- W3030836342 hasRelatedWork W2793288038 @default.
- W3030836342 hasRelatedWork W2996359675 @default.
- W3030836342 hasRelatedWork W3031494291 @default.
- W3030836342 hasRelatedWork W3141924892 @default.
- W3030836342 hasVolume "40" @default.
- W3030836342 isParatext "false" @default.
- W3030836342 isRetracted "false" @default.
- W3030836342 magId "3030836342" @default.
- W3030836342 workType "article" @default.