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• W3030870242 abstract "Objective To improve the management of dyspepsia by analyzing the clinical characters of dyspeptic symptoms in Shanghai patients. Methods Seven hundreds and eighty-two dyspeptic patients completed a questionnaire of dyspepsia, including 12 previously validated common upper abdominal ~symptoms with scoring of severity. The clinical characters of dyspepsia such as alarm symptoms, the ~relationship between symptoms and meals were then analyzed. Results Among 782 dyspeptic patients, 543 cases (69.4%) were functional dyspepsia (FD), and 239 (30.6%) organic dyspepsia (OD). The proportion of males was significantly higher in OD group than that in FD group. There was no difference in average dyspepsia scores between the two dyspeptic groups (21.5 vs. 20.4, P0.05), but epigastric pain and epigastric pain before meals were more often presented in OD patients (2.65±1.11 vs. 2.16~±0.92 , 2.26±1.26 vs. 1.79±0.92,P0.05). In 45.2% of OD patients and 47.7% of FD patients, the severity of symptoms was not related with meal, respectively. In subgroups of ulcer-like, ~dysmotility like and non-specific dyspepsia, the proportion of patients with symptoms not related to meal was ~59.6 %, 50.9% and 35.2%, respectively. About 2.5% (6/239) of OD patients presented with ~progressing dysphagia, compared with 2.8% (15/543) of FD patients presented with intermittent ~dysphagia . About 8.8% (21/239) of OD patients reported severe weight loss accompanied with other ~alarm symptoms, compared with 5.9% (32/543) of FD patients not with other alarm symptoms. Shifting of symptom subtypes during the follow-up period was found in 13.8% of FD patients. The infection rate of Helicobacter pylori was higher in OD group than that in FD group (53.1% vs. 42.2%, P~0.01 ), but no difference was found among the three subgroups of FD patients (P0.05). Halitosis was more often in dyspeptic patients with Helicobacter pylori infection (44.9% vs. 17.0% in OD, ~47.3% vs. ~25.4 % in FD, P0.01).Conclusions When dyspepsia patients present with epigastric pain or epigastric pain before meals, attention should be paid to a diagnosis of OD. Intermittent dysphagia, weight loss not ~accompanied with other alarm symptoms and halitosis (more often in patients with Helicobacter pylori ~infection ) may be regarded as the relatively special symptoms of dyspepsia in a part of FD patients. In FD, the severity of dyspepsia symptoms were not related to meals in half of patients, and symptom ~subtypes may shift over time, thus all of these add difficulty to the management of FD." @default.
• W3030870242 created "2020-06-05" @default.
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• W3030870242 date "2005-01-01" @default.
• W3030870242 modified "2023-10-17" @default.
• W3030870242 title "Analysis of clinical characters of dyspeptic symptoms in Shanghai patients" @default.
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