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- W3030871043 abstract "ObjectiveTo evaluate the development of cerebral sulci and gyrus in fetuses with conotruncal defect(CTD) at the second and third trimester by ultrasound, and to improve clinician′s understanding of the cerebral cortical development in fetuses with CTD.MethodsThe study was conducted at Shenzhen Maternity and Child Healthcare Hospital Affiliated to Southern Medicial University from December 2015 to January 2017, enrolled 180 women with single fetus, among whom 60 fetuses with CTD and gestational age between 20 weeks to 33+ 6 weeks were diagnosed by echocardiographic examination. CTD included persistent truncus arteriosous, tetralogy of fallot, transpofition of the great arteries and double outlet of right ventricle. Evaluation indexes of cerebral sulci and gyrus included depth and angle of parietooccipital sulcus, width and depth of sylvian fissure, uncovered width of insular, uncovered insular ratio, depth of calcarine sulcus, head circumference; evaluation indexes of hemodynamics included umbilical artery resistance index, umbilical artery pulsation index, middle cerebral artery resistance index, middle cerebral artery pulsation index, the cerebral-to-placental resistance ratio and the cerebroplacental pulsation ratio. Above indexes were measured for statistical analysis.ResultsAt the whole gestational age in the study, depth of parietooccipital sulcus and width of sylvian fissure in CTD fetuses were smaller than those in the control group, uncovered insular ratio was larger than that in the normal group(P<0.05); middle cerebral artery resistance index, middle cerebral artery pulsation index and the cerebroplacental pulsation ratio in CTD fetuses were lower than those of the control group (P<0.05).ConclusionsThe change of hemodynamics in fetuses with CTD may be one of the reasons that fetuses with CTD have cerebral cortical hypoevolutism.Key words: Ultrasonography, prenatal; Fetus; Conotruncal defects; Sulci and gyrus" @default.
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- W3030871043 date "2017-06-25" @default.
- W3030871043 modified "2023-09-25" @default.
- W3030871043 title "The prenatal ultrasonic study of cerebral sulci and gyrus development in fetuses with conotruncal defects at the second and third trimester" @default.
- W3030871043 doi "https://doi.org/10.3760/cma.j.issn.1004-4477.2017.06.010" @default.
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